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JEOL Cryo TEMs for Structural Biology


High contrast imaging. Tomography. Montaging. Cryo-electron microscopy. Thin film Zernike phase plate technology. Remote and automated operation.

These capabilities, combined with ultrahigh resolution and ease of use, distinguish JEOL TEM instrumentation for structural biology research. JEOL customers are pioneering discoveries in infectious diseases, bacteria, deadly viruses, and complex neuronal structures. JEOL TEMs are located in some of the most prestigious research labs in the world.

Today’s JEOL TEMs are the result of more than six decades of electron optics expertise, research partnerships, and advances in TEM technology by world-renowned scientists.

JEOL offers a range of high performance TEMs, from 300kV and 200kV models with in-column energy filter for leading edge research, to a 120keV TEM for routine sample screening:

The JEM-3200FS and FSC combine high resolution and zero-loss sample imaging with analytical performance in a 300kV class analytical TEM. The FSC model features a cooled liquid nitrogen/helium cryogenic stage. Both TEMs feature an in-column Omega energy filter and highly stable Piezo stage.

The JEM-2200FS achieves rotation-free energy-filtered TEM images and diffraction patterns over a wide range of magnifications and camera lengths. This 200kV TEM features a high-precision digital CCD camera, a piezo-controlled goniometer stage for precise specimen movement, and a stable, vibration-proof platform.

The JEM-1400, the popular and versatile JEOL 120kV TEM, can be configured for either high contrast imaging or scanning transmission electron microscopic (S/TEM) analysis.

To learn more about how JEOL TEMs have revolutionized biological research with phase plate technology, or for a bibliography of papers and proceedings published on this topic, please complete the form below.

Images in collage: JEOL JEM-2100F and JEM-3200FSC TEM at Baylor College of Medicine (photos by Ian Rees NCMI); 3D reconstruction showing DNA packaging in virus capsid (Courtesy of Life Sciences Division, Lawrence Berkeley National Laboratory); Tomography of resin-embedded basal bodies (Courtesy of Dr. Geimer, University of Bayreuth); Stained Mouse retina showing more than 70 types of neurons, and microneuroma on a mouse retina - montage of more than 1000 unattended frame captures in just three hours (Marc Lab, Moran Eye Center, University of Utah); 3D reconstruction of bacteriophage, and structure of GroEL, a molecular machine that aids protein folding (Courtesy of Dr. Wah Chiu, Baylor College of Medicine); JEOL JEM-1400 TEM.

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