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Spiral TOF™ Monoisotopic Precursor Ion Selection

TOF/TOF Monoisotopic Precursor Ion Selection

The flight path to the ion gate is 15 m, more than one order of magnitude longer than that of conventional MALDI‑TOF/TOF instruments, thus allowing monoisotopic selection of the precursor ions. As a result, all product ions produced from a monoisotopically selected precursor ion are also monoisotopic, making the interpretation of the product ion spectrum much simpler.

Additionally, two fragmentation pathways that produce two product ion peaks only one or two m/z units apart can be clearly distinguished with confidence. This is not possible with conventional MALDI‑TOF/TOF instruments with which monoisotopic selection of precursor ions is not possible.

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