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JEOL USA Automated Data Acquisition (JADAS)

JEOL Automated Data Acquisition System (JADAS) software was developed in collaboration with NCMI Baylor College of Medicine for cryoelectron microscopy. Using JADAS, researchers can customize parameters for ice-embedded macromolecular complexes under low dose conditions. The software acquires large quantities of high quality data without operator intervention. The sample stage moves sequentially to create a complete grid atlas. The software evaluates ice thickness, defocus and drift, among other parameters, before acquiring the high resolution data.

Left: Recipe editor in JADAS
Right: Icosahedral reconstruction of a bacteriophage epsilon-15 at sub-nanometer resolution using cryo-EM images acquired by JADAS