JEOL Resourceshttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-DownloadsSolid State Battery Notehttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/solid-state-battery-noteYokogushi (Cross-platform Analysis)Tue, 05 Mar 2024 09:57:55 GMTThis Solid-state battery Note has been created to provide solutions and reference information for research and development of solid-state batteries evolving from the lithium ion batteries (LIBs).<p>Battery cells are essential in modern life as they are extensively used in mobile phones, personal computers, and even in automobiles as the power source in recent years.<br /> The shift to battery vehicles (BEV) is rapidly advancing worldwide in order to achieve carbon neutrality by 2050 which is to “reduce overall greenhouse gas emissions to zero”. The research and development on rechargeable battery cells that can be used repeatedly, are progressing for the use of power source of BEV and larger energy storage system (ESS). To improve both the performance and quality of these battery cells, analyses and evaluations by using various high-performance evaluation instruments are required.<br /> JEOL offers a wide variety of analytical instruments available for morphological observations, surface analyses, structure analyses, and chemical analyses at micro- to nano-scales for the purpose of research, development, and quality improvement.<br /> This Solid-state battery Note has been created with the samples provided by Prof. Atsunori Matsuda, Toyohashi University of Technology (Department of Electrical and Electronic Information Engineering), to provide solutions and reference information for research and development of solid-state batteries evolving from the lithium ion batteries (LIBs).</p> Chenometric Tool - Gateway to Chenometrics with NMR Datahttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/chenometric-tool-gateway-to-chenometrics-with-nmr-dataNMR ApplicationsThu, 24 Aug 2023 07:44:26 GMTChenometrics is a discipline that utilizes data mining techniques, including dimensionality reduction, discrimination, visualization, and regression, to extract information from extensive sets of experimental analytical data. NMR spectroscopy, a highly quantitative and reproducible technique, allows for non-invasive analysis of chemical species with minimal sample preparation. This is particularly advantageous for data mining, as NMR spectra, including series of 1H NMR spectra of biological samples, are commonly employed as input for multivariate analysis by converting series of 1D NMR spectra into a matrix. The 'Chemospec' package in the R language for statistical computing serves as the engine for multivariate analysis. When the 'Chempspec' package is installed, the Delta software offers a seamless user interface for exploratory multivariate analysis.<p>Applications note NM220007</p> <p>Chenometrics is a discipline that utilizes data mining techniques, including dimensionality reduction, discrimination, visualization, and regression, to extract information from extensive sets of experimental analytical data. NMR spectroscopy, a highly quantitative and reproducible technique, allows for non-invasive analysis of chemical species with minimal sample preparation. This is particularly advantageous for data mining, as NMR spectra, including series of <sup>1</sup>H NMR spectra of biological samples, are commonly employed as input for multivariate analysis by converting series of 1D NMR spectra into a matrix. The 'Chemospec' package in the R language for statistical computing serves as the engine for multivariate analysis. When the 'Chempspec' package is installed, the Delta software offers a seamless user interface for exploratory multivariate analysis.</p> Diffusion Analysis Multi - Multiple Exponential Function Fitting for PFG-NMR datahttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/diffusion-analysis-multi-multiple-exponential-function-fitting-for-pfg-nmr-dataNMR ApplicationsThu, 24 Aug 2023 07:32:59 GMTPulsed-Field Gradient Nuclear Magnetic Resonance (PFG-NMR) is utilized to analyze the self-diffusion of molecules and ions. The self-diffusion coefficient (D) in PFG-NMR is determined by recording the decay of signal intensity through a series of experiments using either Pulsed Gradient Spin Echo (PGSE) or Pulsed Gradient Stimulated Echo (PGSTE) sequences with varying gradient strengths (G). The decay of signal intensity is subsequently analyzed using curve fitting or inverse Laplace transformation methods. The Delta NMR software provides a curve analysis tool that supports the fitting of PFG-NMR data. Versions 5.3.3 and earlier of the Delta NMR software support curve fitting using a model that assumes a single self-diffusion coefficient contributing to the decay. However, starting from the Delta NMR software version 6.0 and onwards, there is support for curve fitting using the "Diffusion Analysis Multi" feature. This feature enables the analysis to account for multiple self-diffusion coefficients during the curve fitting process.<p>Applications note NM220006E</p> <p>Pulsed-Field Gradient Nuclear Magnetic Resonance (PFG-NMR) is utilized to analyze the self-diffusion of molecules and ions. The self-diffusion coefficient (D) in PFG-NMR is determined by recording the decay of signal intensity through a series of experiments using either Pulsed Gradient Spin Echo (PGSE) or Pulsed Gradient Stimulated Echo (PGSTE) sequences with varying gradient strengths (G). The decay of signal intensity is subsequently analyzed using curve fitting or inverse Laplace transformation methods. The Delta NMR software provides a curve analysis tool that supports the fitting of PFG-NMR data. Versions 5.3.3 and earlier of the Delta NMR software support curve fitting using a model that assumes a single self-diffusion coefficient contributing to the decay. However, starting from the Delta NMR software version 6.0 and onwards, there is support for curve fitting using the "Diffusion Analysis Multi" feature. This feature enables the analysis to account for multiple self-diffusion coefficients during the curve fitting process.</p> Double Stimulated Echo (DSTE) Experiments for Thermal Convection Compensation in PFG-NMRhttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/double-stimulated-echo-dste-experiments-for-thermal-convection-compensation-in-pfg-nmrNMR ApplicationsThu, 24 Aug 2023 07:21:27 GMTPulsed-Field Gradient NMR (PFG-NMR) is utilized for analyzing the self-diffusion of molecules and ions, which are commonly referred to as 'particles' in this context. The translation of particles by thermal convection significantly impacts the decay curve in PFG-NMR experiments, particularly when dealing with solution and liquid samples. In cases where the convection-induced translation is substantial, the decay curve exhibits a cosine-like behavior, leading to an apparent increase in the self-diffusion coefficient compared to the actual value. Additionally, the decay curves may become distorted, occasionally resulting in the appearance of signals in negative phase. To address this convection artifact in PFG-NMR, Double Stimulated Echo (DSTE) experiments are specifically designed and employed.<p>Applications note NM220005</p> <p>Pulsed-Field Gradient NMR (PFG-NMR) is utilized for analyzing the self-diffusion of molecules and ions, which are commonly referred to as 'particles' in this context. The translation of particles by thermal convection significantly impacts the decay curve in PFG-NMR experiments, particularly when dealing with solution and liquid samples. In cases where the convection-induced translation is substantial, the decay curve exhibits a cosine-like behavior, leading to an apparent increase in the self-diffusion coefficient compared to the actual value. Additionally, the decay curves may become distorted, occasionally resulting in the appearance of signals in negative phase. To address this convection artifact in PFG-NMR, Double Stimulated Echo (DSTE) experiments are specifically designed and employed.</p> Multiple-Resonance Measurements on ECZ Luminous_NM220004Ehttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/multiple-resonance-measurements-on-ecz-luminousnm220004eROYALPROBE HFXMon, 24 Oct 2022 09:53:29 GMTA standard NMR system has one high-frequency channel and a low-frequency one, the ECZL series has a new function called the Multi Frequency Drive System.<p>Fig. 2 shows an example of <sup>1</sup>H, <sup>13</sup>C, and <sup>31</sup>P triple resonance measurement when using an HCX triple-resonance probe. As shown in Fig 2 b), the doublets collapse into singlets by the simultaneous <sup>1</sup>H and <sup>31</sup>P decoupling. This increases sensitivity and makes the analysis of the spectrum easier. Fig. 3 shows an example of <sup>1</sup>H, <sup>13</sup>C and <sup>15</sup>N triple-resonance measurement performed on a labeled protein using an HCN triple-resonance probe. Both triple-resonance measurements were performed on a standard 2-channel JNM-ECZL600G instrument. It is clear that the triple-resonance measurements were properly performed.</p> <div class="row"> <div class="col-md-6" style="text-align: center;"><img alt="Fig. 2: a) 13C{1H} and b) 13C{1H}{31P} spectra of diethylmethylphosphonate in CDCl3 by HCX probe" src="https://www.jeolusa.com/Portals/2/resources_ai/783/nm220004_02e.jpg" /><br /> <strong>Fig. 2: a) <sup>13</sup>C{1H} and b) <sup>13</sup>C{1H}{<sup>31</sup>P} spectra of diethylmethylphosphonate in CDCl<sub>3</sub> by HCX probe</strong></div> <div class="col-md-6" style="text-align: center;"><img alt="Fig. 3: 3D HNCOCO spectrum of 13C/15N labeled Ubiquitin in 90% H2O / 10% D2O by HCN probe" src="https://www.jeolusa.com/Portals/2/resources_ai/783/nm220004_03e.jpg" /><br /> <strong>Fig. 3: 3D HNCOCO spectrum of <sup>13</sup>C/<sup>15</sup>N labeled Ubiquitin in 90% H<sub>2</sub>O / 10% D<sub>2</sub>O by HCN probe</strong></div> </div> Introduction of a method to analyze 3D structures using homonuclear couplings_NM210004Ehttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/introduction-of-a-method-to-analyze-3d-structures-using-homonuclear-couplingsnm210004eNuclear Magnetic Resonance (NMR)Mon, 29 Nov 2021 10:14:39 GMTStructural analysis by NMR can provide not only a planar molecular structure but also three-dimensional structural information. In this Note, we describe a method for obtaining information on dihedral angles by using 1H-1H coupling constants (JHH values). For example, hydrogen atoms attached to a cyclohexane ring are either located in axial or equatorial positions in respect to the cyclohexane ring (Fig. 1). The dihedral angles between vicinal protons are known to be ∠Hax-C-C-Hax ≈ 180°, ∠Hax-C-Heq ≈ 60°, and ∠Heq-C-C-Heq ≈ 60°. If we look at the Karplus curve shown in Fig. 2, we can see that 3JHH of around 4 Hz can be expected in the case of the dihedral angle of 60°, while 3JHH of around 13 Hz corresponds to the dihedral angle of 180°. In reality, 3JHH values depend on substituents attached to the cyclohexane ring in substituted cyclohexanes, so the analysis is not straightforward, but the basic trend of having a larger J-value for a 180° dihedral angle compared to a 60° dihedral angle remains unchanged. Therefore, from the value of 3JHH of the methylene protons, it is possible to differentiate between the dihedral angle of 60° or 180°.<p>Structural analysis by NMR can provide not only a planar molecular structure but also three-dimensional structural information. In this Note, we describe a method for obtaining information on dihedral angles by using <sup>1</sup>H-<sup>1</sup>H coupling constants (<em>J</em><sub>HH</sub> values). For example, hydrogen atoms attached to a cyclohexane ring are either located in axial or equatorial positions in respect to the cyclohexane ring (Fig. 1). The dihedral angles between vicinal protons are known to be ∠H<sub>ax</sub>-C-C-H<sub>ax</sub> ≈ 180°, ∠H<sub>ax</sub>-C-H<sub>eq</sub> ≈ 60°, and ∠H<sub>eq</sub>-C-C-H<sub>eq</sub> ≈ 60°. If we look at the Karplus curve shown in Fig. 2, we can see that <sup>3</sup><em>J</em><sub>HH</sub> of around 4 Hz can be expected in the case of the dihedral angle of 60°, while <sup>3</sup><em>J</em><sub>HH</sub> of around 13 Hz corresponds to the dihedral angle of 180°. In reality, <sup>3</sup><em>J</em><sub>HH</sub> values depend on substituents attached to the cyclohexane ring in substituted cyclohexanes, so the analysis is not straightforward, but the basic trend of having a larger <em>J</em>-value for a 180° dihedral angle compared to a 60° dihedral angle remains unchanged. Therefore, from the value of <sup>3</sup><em>J</em><sub>HH</sub> of the methylene protons, it is possible to differentiate between the dihedral angle of 60° or 180°.</p> <h3>Please click below to download and read more.</h3> 20 T/m high field gradient strength diffusion measurement system_NM210006Ehttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/20-tm-high-field-gradient-strength-diffusion-measurement-systemnm210006eNuclear Magnetic Resonance (NMR)Mon, 29 Nov 2021 09:35:34 GMTThe new generation diffusion probe is specially designed for diffusion applications that requires a large magnetic field gradient. By improving the design around the coil, the recovery time after field gradient pulse has been significantly shortened compared to the conventional model. Using a newly developed 50A bipolar magnetic field gradient power supply, a magnetic field gradient of 20 T/m (2000 G/cm) can be applied, making it possible to measure diffusion coefficients on the order of 10-14 m2/s. This system is ideal for measuring the diffusion of ions in solid electrolytes.<h2>Diffusion measurement of Lithium ions in solid electrolyte</h2> <p>Since the <sup>7</sup>Li signal of lithium ions in solid electrolyte often has a short <em>T</em><sub>2</sub> relaxation time, the magnetic field gradient pulse (PFG) width applied to the transverse magnetization cannot be sufficiently long. Since the diffusion coefficients of solid electrolytes are also small, it is necessary to be able to apply a large amplitude of PFG in a short time in order to obtain attenuation of the echo signal due to diffusion.<br /> Fig. 1 shows <sup>7</sup>Li echo signal decay plots of solid oxide electrolyte LLTZO (<em>D</em>=2.1x10<sup>-13</sup> m<sup>2</sup>/s @30°C) using 30A (12 T/m) and 50A (20 T/m) magnetic field gradient power supplies. The use of the 50A power supply makes it possible to calculate the diffusion coefficient more accurately and to measure the diffusion of systems with smaller diffusion coefficients.</p> <div class="row"> <div class="col-md-6"> <table> <tbody> <tr> <td>Sample:</td> <td>LLTZO single crystal</td> </tr> <tr> <td>Instruments:</td> <td>JNM-ECZ500R, Diffusion probe</td> </tr> <tr> <td valign="top">Method:</td> <td><sup>7</sup>Li Stimulated Echo<br /> Diffusion time = 150ms<br /> PFG width = 2.5 ms<br /> Temperature = 30 °C</td> </tr> </tbody> </table> </div> <div class="col-md-6"><img alt="" src="https://jeolusa.s3.amazonaws.com/resources_ai/747/2108_3.png?AWSAccessKeyId=AKIAQJOI4KIAZPDULHNL&Expires=2145934800&Signature=wSnqaAF03VPxaDa8sVTRYcvvOGo%3D" /><br /> Fig. 1 <sup>7</sup>Li signal decay plots of a single crystal LLTZO as a function of<br /> gradient strength by using 30A and 50A gradient power supplies.</div> </div> <p>Courtesy of Dr. Naoaki Kuwata (NIMS)<br /> and Dr. Junji Akimoto (AIST)</p> Lithium Ion Battery Notehttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/lithium-ion-battery-noteNuclear Magnetic Resonance (NMR)Mon, 27 Jul 2020 21:13:53 GMTThe applications for lithium ion batteries (LIB) cover a wide range, from power sources for personal computers and mobile devices to automobiles, and there is always a demand for even better performance and safety. In order to ensure the performance and quality of LIB, analysis and evaluation using high-performance assessment systems is necessary. JEOL offers a full line-up of equipment to support the development of new LIB technologies and to improve product quality, including instruments for morphology observation and surface analysis, chemical analysis systems to perform structural analysis on a molecular level, as well as fabrication systems to create high-performance coatings and powders. This LIB note offers solutions for researchers and engineers who are looking for the best equipment for their application.<p>The applications for lithium ion batteries (LIB) cover a wide range, from power sources for personal computers and mobile devices to automobiles, and there is always a demand for even better performance and safety. In order to ensure the performance and quality of LIB, analysis and evaluation using high-performance assessment systems is necessary. JEOL offers a full line-up of equipment to support the development of new LIB technologies and to improve product quality, including instruments for morphology observation and surface analysis, chemical analysis systems to perform structural analysis on a molecular level, as well as fabrication systems to create high-performance coatings and powders. This LIB note offers solutions for researchers and engineers who are looking for the best equipment for their application.</p> Food Analysis Solutionshttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/food-analysis-solutionsNuclear Magnetic Resonance (NMR)Mon, 27 Jul 2020 21:08:18 GMTJEOL offers numerous analytical tools to support both "food safety & security" as well as various evaluations of primary, secondary and tertiary functions of foodstuffs which are useful for a wide range of users associated with this field. This Foodnote introduces the features of each of the instruments and actual analysis examples, and is designed for researchers and engineers who are considering purchases of instruments. This brochure also presents comprehensive evaluations and analysis solutions that can be achieved with combinations of multiple instruments.<p>JEOL offers numerous analytical tools to support both "food safety & security" as well as various evaluations of primary, secondary and tertiary functions of foodstuffs which are useful for a wide range of users associated with this field.</p> <p>This Foodnote introduces the features of each of the instruments and actual analysis examples, and is designed for researchers and engineers who are considering purchases of instruments. This brochure also presents comprehensive evaluations and analysis solutions that can be achieved with combinations of multiple instruments.</p> Bio Solutionshttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/bio-solutionsNuclear Magnetic Resonance (NMR)Mon, 27 Jul 2020 21:02:33 GMTThis Bionote presents an overview of the basics, namely principles and features of various instruments, as well as application examples using numerous optional attachments. We hope that the Bionote will assist researchers and engineers who intend to perform analyses in finding and exploring new approaches.<p>Instrumental analysis has contributed to the progress of biological science, through the observation of morpohology, the chemical analysis of compounds, the elucidation of amino acid sequences of proteins, etc. Furthermore, this progress has been accelerated by the development of analytical methods, which are used in diverse fields like medical science, agriculture, food and biotechnology, as well as the basic research work like physiology, biochemistry and genetics.</p> <p>This Bionote presents an overview of the basics, namely principles and features of various instruments, as well as application examples using numerous optional attachments. We hope that the Bionote will assist researchers and engineers who intend to perform analyses in finding and exploring new approaches.</p>