JEOL Resourceshttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-DownloadsMeasurement of boroxine cage using JMS-S3000 SpiralTOFhttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/measurement-of-boroxine-cage-using-jms-s3000-spiraltofMALDI SpiralTOF™Thu, 24 Aug 2023 07:12:13 GMTBoroxine cages are nanometer-sized covalent cage-like molecules that utilize beroxine formation reactions. Such molecular-sized hollow structures can contain other molecules. Encapsulated molecules sometimes change their properties significantly, and various applications using them are being investigated. One of the methods for confirming the synthesis of boroxine cages is mass spectrometry, and MALDI-TOFMS is suitable because it can ionize a wide range of compounds mainly as single-charge ions. The JMS-S3000 SpiralTOF™ achieves a long flight distance of 17 m due to its unique spiral ion trajectory, and can measure low-molecular-weight compounds ionized by the MALDI method with high mass resolution and high mass accuracy. In this report, we report the accurate mass measurement of the boroxine caged 12-mer.<p>MSTips No. 369</p> <p>Boroxine cages are nanometer-sized covalent cage-like molecules that utilize beroxine formation reactions. Such molecular-sized hollow structures can contain other molecules. Encapsulated molecules sometimes change their properties significantly, and various applications using them are being investigated. One of the methods for confirming the synthesis of boroxine cages is mass spectrometry, and MALDI-TOFMS is suitable because it can ionize a wide range of compounds mainly as single-charge ions. The JMS-S3000 SpiralTOF™ achieves a long flight distance of 17 m due to its unique spiral ion trajectory, and can measure low-molecular-weight compounds ionized by the MALDI method with high mass resolution and high mass accuracy. In this report, we report the accurate mass measurement of the boroxine caged 12-mer. </p> Development of peak extraction method from a high-resolution MALDI-TOF mass spectrum by machine learning focusing on peak shape, and an application to synthetic polymer analysishttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/development-of-peak-extraction-method-from-a-high-resolution-maldi-tof-mass-spectrum-by-machine-learning-focusing-on-peak-shape-and-an-application-to-synthMALDI SpiralTOF™Thu, 24 Aug 2023 07:01:40 GMTMatrix-assisted laser desorption/ionization time-of-flight mass spectrometers (MALDI-TOFMS) is a powerful tool in the analysis of polymers. High-resolution MALDI-TOFMS facilitates the identification of polymer series by the elemental composition of repeating units and end groups, and allows the calculation of the molecular weight distribution of polymers from the ionic intensity distribution. In actual industrial material analysis, mixtures of polymers with different molecular weight disributions and end groups are analyzed.<p>MSTips No. 352</p> <p>Matrix-assisted laser desorption/ionization time-of-flight mass spectrometers (MALDI-TOFMS) is a powerful tool in the analysis of polymers. High-resolution MALDI-TOFMS facilitates the identification of polymer series by the elemental composition of repeating units and end groups, and allows the calculation of the molecular weight distribution of polymers from the ionic intensity distribution. In actual industrial material analysis, mixtures of polymers with different molecular weight disributions and end groups are analyzed.</p> JMS-S3000 SpiralTOF™-plus Product Brochurehttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/jms-s3000-spiraltof-plus-product-brochure1Mass Spectrometry (MS)Tue, 15 Feb 2022 10:14:44 GMTThe JMS-S3000 SpiralTOF™-plus Ultra-High Mass Resolution MALDI-TOFMS System time-of-flight optics design utilizes a figure-eight ion trajectory to allow a 17m flight path to fit in an extremely small console.<p>The <strong>JMS-S3000 SpiralTOF™-plus Ultra-High Mass Resolution MALDI-TOFMS</strong> System time-of-flight optics design utilizes a figure-eight ion trajectory to allow a 17m flight path to fit in an extremely small console. This exceptionally long flight path results in an ultrahigh resolving power of >75,000 and sub-ppm mass accuracy. The versatile SpiralTOF is an essential research tool for your state-of-the-art MS analyses of functional synthetic polymers, material science and biomolecules.</p> <h3>Click Below to Download</h3> Analysis of Degraded Polymethyl Methacrylate by UV Irradiation - MSTips 324https://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/analysis-of-degraded-polymethyl-methacrylate-by-uv-irradiation-mstips-324Mass Spectrometry (MS)Mon, 13 Dec 2021 12:02:49 GMTPolymers can be degraded by the effects of light, oxygen, heat, etc. so it is important to understand how the polymer structures change during degradation. Pyrolysis gas chromatograph quadrupole mass spectrometer (Py-GC-QMS) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometer (MALDI-TOFMS) are powerful tools for analyzing polymeric materials. Py-GC-QMS is a method that instantaneously heats a sample with a pyrolyzer and then analyzes the pyrolysis products by GC-MS. Since most of the pyrolysis products are related to monomers and dimers, this technique allows for easy identification of the polymer substructures which is useful for identifying changes to the polymer when degradation occurs. MALDI-TOFMS involves a soft ionization technique that can directly ionize and analyze the intact polymer molecules and often produces singly-charged ions even for high molecular weight compounds. As a result, the m/z axis of the mass spectrum is equal to the mass of the ions, thus making it easy to interpret polymer distributions. Additionally, when MALDI is used with a high-resolution TOFMS, the accurate mass of each ion in the polymer series can be used to calculate their elemental compositions. Moreover, the molecular weight distribution of polymers can be calculated from the ion intensity distribution. In this work, we used Py-GC-QMS and high-resolution MALDI-TOFMS to evaluate the effects of UV irradiation on polymethyl methacrylate (PMMA).<h3>Introduction</h3> <p>Polymers can be degraded by the effects of light, oxygen, heat, etc. so it is important to understand how the polymer structures change during degradation. Pyrolysis gas chromatograph quadrupole mass spectrometer (Py-GC-QMS) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometer (MALDI-TOFMS) are powerful tools for analyzing polymeric materials.<br /> Py-GC-QMS is a method that instantaneously heats a sample with a pyrolyzer and then analyzes the pyrolysis products by GC-MS. Since most of the pyrolysis products are related to monomers and dimers, this technique allows for easy identification of the polymer substructures which is useful for identifying changes to the polymer when degradation occurs. MALDI-TOFMS involves a soft ionization technique that can directly ionize and analyze the intact polymer molecules and often produces singly-charged ions even for high molecular weight compounds.<br /> As a result, the <em>m/z</em> axis of the mass spectrum is equal to the mass of the ions, thus making it easy to interpret polymer distributions. Additionally, when MALDI is used with a high-resolution TOFMS, the accurate mass of each ion in the polymer series can be used to calculate their elemental compositions. Moreover, the molecular weight distribution of polymers can be calculated from the ion intensity distribution. In this work, we used Py-GC-QMS and high-resolution MALDI-TOFMS to evaluate the effects of UV irradiation on polymethyl methacrylate (PMMA).</p> <h3>To read more, please click below to download the application note.</h3> MALDI imaging brochurehttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/maldi-imaging-brochureMass Spectrometry (MS)Fri, 19 Mar 2021 13:04:15 GMTAdvanced statistical analysis of MALDI MS imaging data required by SpiralTOF-plus while taking full advantage of its high mass-resolving power.<p>Advanced statistical analysis of MALDI MS imaging data required by SpiralTOF-plus while taking full advantage of its high mass-resolving power.</p> <h3>Click Below To View The Brochure.</h3> SpiralTOF-plus Polymer Mass Spectra Collectionhttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/spiraltof-plus-polymer-mass-spectra-collectionMass Spectrometry (MS)Thu, 11 Mar 2021 11:17:27 GMTApplications concerning Polymers using the SpiralTOF.<p>Applications concerning Polymers using the SpiralTOF.</p> <h3>Please click below to Download</h3> SpiralTOF Polymers, Materials & Chemistry Applications Notebook 2020https://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/spiraltof-polymers-materials-chemistry-applications-notebook-2020Mass Spectrometry (MS)Thu, 11 Mar 2021 11:15:23 GMTApplications concerning Polymers, Materials & Chemistry using the SpiralTOF.<p>Applications concerning  Polymers, Materials & Chemistry using the SpiralTOF.</p> <h3>Please click below to Download</h3> SpiralTOF Life Science Applications Notebook 2020https://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/spiraltof-life-science-applications-notebookMass Spectrometry (MS)Thu, 11 Mar 2021 11:12:35 GMTApplications for Life Science using the SpiralTOF.<p>Applications for Life Science using the SpiralTOF.</p> <h3>Please click below to Download.</h3> Food Analysis Solutionshttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/food-analysis-solutionsNuclear Magnetic Resonance (NMR)Mon, 27 Jul 2020 21:08:18 GMTJEOL offers numerous analytical tools to support both "food safety & security" as well as various evaluations of primary, secondary and tertiary functions of foodstuffs which are useful for a wide range of users associated with this field. This Foodnote introduces the features of each of the instruments and actual analysis examples, and is designed for researchers and engineers who are considering purchases of instruments. This brochure also presents comprehensive evaluations and analysis solutions that can be achieved with combinations of multiple instruments.<p>JEOL offers numerous analytical tools to support both "food safety & security" as well as various evaluations of primary, secondary and tertiary functions of foodstuffs which are useful for a wide range of users associated with this field.</p> <p>This Foodnote introduces the features of each of the instruments and actual analysis examples, and is designed for researchers and engineers who are considering purchases of instruments. This brochure also presents comprehensive evaluations and analysis solutions that can be achieved with combinations of multiple instruments.</p> Bio Solutionshttps://www.jeolusa.com/RESOURCES/Analytical-Instruments/Documents-Downloads/bio-solutionsNuclear Magnetic Resonance (NMR)Mon, 27 Jul 2020 21:02:33 GMTThis Bionote presents an overview of the basics, namely principles and features of various instruments, as well as application examples using numerous optional attachments. We hope that the Bionote will assist researchers and engineers who intend to perform analyses in finding and exploring new approaches.<p>Instrumental analysis has contributed to the progress of biological science, through the observation of morpohology, the chemical analysis of compounds, the elucidation of amino acid sequences of proteins, etc. Furthermore, this progress has been accelerated by the development of analytical methods, which are used in diverse fields like medical science, agriculture, food and biotechnology, as well as the basic research work like physiology, biochemistry and genetics.</p> <p>This Bionote presents an overview of the basics, namely principles and features of various instruments, as well as application examples using numerous optional attachments. We hope that the Bionote will assist researchers and engineers who intend to perform analyses in finding and exploring new approaches.</p>