MALDI-TOFMS

The JMS-S3000 SpiralTOF™-plus 3.0 is a MALDI-TOFMS that uses innovative SpiralTOF ion optics that has been updated to extend the mass range of this high resolution system. The JMS-S3000 defines a new standard in MALDI-TOFMS performance and provides state-of-the-art analytical solutions for a wide range of research areas such as functional synthetic polymers, materials science, and biomolecules.

The combination of the JMS-S3000 SpiralTOF™-plus 3.0's high mass resolution, high mass accuracy, and wide dynamic range with the msRepeatFinder polymer analysis software makes it the most powerful polymer analysis system.

MALDI MS imaging was initially developed to focus on high molecular weight compounds such as proteins and peptides. However, with the expanding applications of MALDI MS imaging, the interests have shifted to include smaller molecules such as lipids, pharmaceuticals, and pharmaceutical metabolites. Conventional MALDI-reflectron TOFMS has difficulty discerning small molecule signals from matrix molecules. In the case of MALDI MS imaging, signals from unwanted molecules on the specimen surface will often interfere with signals from the target analytes. High selectivity by means of high mass-resolving power is essential for obtaining reliable target analyte spatial distributions. The SpiralTOF™-plus 3.0 with its high mass-resolving power is indispensable for MALDI MS imaging.

MALDI-TOFMS is highly effective for analyzing biomolecules due to its soft ionization and high sensitivity. It enables rapid, accurate profiling of proteins, peptides, and glycans, facilitating biomarker discovery in clinical research. Minimal sample preparation and high throughput make it ideal for diagnostics and disease-related studies.

MALDI-TOFMS enables detailed characterization of synthetic polymers, including molecular weight distribution, end-group analysis, and copolymer composition. Its high sensitivity and soft ionization allow intact analysis of large macromolecules with minimal fragmentation, supporting research, quality control, and structural elucidation in polymer science and material development.

MALDI-TOFMS offers fast and accurate analysis for a wide range of organic synthetic compounds from low-molecular-weight to high-molecular-weight molecules. Its soft ionization preserves structural integrity, enabling precise molecular weight determination and impurity detection. Minimal sample preparation and high sensitivity make it ideal for synthetic chemistry and compound verification.

MALDI-TOFMS enables rapid and sensitive analysis of food and plant samples, identifying compounds such as peptides, lipids, and sugars. Its soft ionization preserves molecular structures, making it ideal for profiling components contained in food. It supports quality control, authenticity testing, and nutritional or functional ingredient studies.