JEOL - a global leader in NMR since the inception of commercial NMR manufacturing

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JEOL - renowned for NMR service and applications support

JEOL - world's fastest spinning speed for NMR

JEOL - world's first liquid NMR probe, switchable between single and dual tune mode

Thinking about NMR?
Trust JEOL for innovation.

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JEOL NMR systems serve some of the world's leading scientists – what can we help you achieve?

NMR Spectroscopy Expertise

For more than 60 years, JEOL has produced high performance Nuclear Magnetic Resonance (NMR) spectrometers for structural analysis of proteins, protein/drug interaction, organic synthesis, and genetic engineering (we have manufactured one of the highest field magnetic fields for NMR in the world). The NMR spectrometer is an indispensable tool for structural determination of molecules, molecular motions, and interactions. JEOL offers a wide range of high-performance NMR spectrometers.  We regularly manufacture a wide range of spectrometers. For Routine NMR experimental use, we offer 400 MHz spectrometers. For experiments requiring more sophisticated measurements, we offer several several models at progressively higher field strengths. Most commonly manufactured are, 500 MHz, 600 MHz, 700 MHz, and 800 MHz NMR Spectrometers. Higher fields are available, please inquire.

What Can We Help You Achieve?

  • Ultra-compact design with fewer components for easy lab room placement
  • Powerful, auto-tuning Royal Probe combines broadband and inverse probe performance which reduces the need for probe changes or purchasing additional probes
  • Easy-access auto samplers (24, 30, 64, 100) – convenient and safe
  • Advanced, user-friendly Delta™ software including free site license
  • Low cost of ownership with an increase in productivity and performance
  • Impressive, new-age look spectrometer console

NMR Systems

ECZ Series of NMR Spectrometers

The ECZ range of NMR spectrometers was created with decades of innovation and practical expertise. There are two models:

  • ECZr Our high end NMR offers wide expandability
  • ECZs Our entry level NMR delivers the same characteristics but in an ultra-compact chassis.

The ECZ NMR spectrometer series is equipped with JEOL’s unique Smart Transceiver System (STS), which uses a fusion of the latest integrated digital circuit and high frequency technologies.

Probes

JEOL has pioneered NMR probes for decades, having attained the world’s fastest spinning speed for NMR with our 0.75mm solid state NMR probe. Our range includes:

Magnets

Manufactured to our specifications by Jastec, our compact JJ magnets feature low cryogen consumption cryostats, extremely small B0 drift characteristics and excellent homogeneity.

Compared to alternative products, the magnet footprint is smaller and the minimum ceiling height is reduced. The consumption of liquid helium has also been reduced and the interval for refill is correspondingly longer.

Software

Delta NMR

JEOL NMR spectrometers feature Delta™, the most advanced NMR software platform available, combining spectrometer control and data management into a single robust application. Delta allows concurrent processing of multiple data sets and simple, seamless operation that unifies NMR data acquisition, processing, visualization, and output.

Walkup NMR

JEOL “Walkup NMR” automates NMR experiments for students or lab personnel running single or multiple samples with the JEOL Nuclear Magnetic Resonance system.

CRAFT COMPLETE REDUCTION TO AMPLITUDE-FREQUENCY TABLE - "SPECTRUM DIRECT TO SPREADSHEET"

Integration of CRAFT with DELTA version 5.3 software allows the JEOL NMR user to automatically and efficiently extract the best data possible from amplitudes and frequency.

NMR Applications

Pharmaceutical development

Regulators now expect pharmaceutical developers to know much more about their drug compounds – and to have this information early in the development process – so NMR has been on the rise. Read more about NMR in pharmaceutical development and download a case study.

With so many drugs on the market now fluorinated, 19F NMR spectroscopy is an important tool for their analysis. JEOL’s ROYAL HFX NMR Probe offers the ability to manipulate the 1H, 19F, and 13C spins simultaneously without the typical loss in performance associated with traditional NMR probes designed for proton-fluorine NMR spectroscopy. Download our ROYAL HFX NMR Probe toolkit to find out more.

Biopharmaceutical development

Biotech companies are increasingly looking to new/improved technology to get the extra insight that comes from combining analytical technologies. NMR is used to inform and optimize cell culture media composition and to monitor nutrient depletion, build-up of metabolites and toxins in the fermentation process. NMR plays an important role in the evaluation of the quality of biologics and also in the approval of biosimilar versions of innovator biologics. Download our Bio app note to find out how JEOL is helping biotech companies to succeed.

Quantitative NMR (qNMR)

NMR has long been a preferred method for organic compound analysis, but it’s quantitative NMR (qNMR) that’s making waves in a field that has so far been reliant upon chromatography for its quantitative analysis requirements.

Food

Food characterization is becoming more important due to food fraud scandals around the world, changing consumer attitudes towards what’s in their foods, increased regulation regarding substantiation of health benefits, scrutiny of labels and the drive for transparency, provenance and sustainability. Food matrices can be complex and difficult to evaluate with techniques such as GC-MS alone. NMR methodology enables primary and secondary metabolites to be identified and quantified, delivering high-throughput spectroscopic and structural information on a wide range of metabolites simultaneously. To find out how NMR and other techniques are being used in the modern food industry, download our food app note.

Lithium ion batteries

To ensure the performance and quality of Lithium ion batteries, analysis and evaluation is done using several types of JEOL instrumentation. NMR is one of the few methods available for directly observing and measuring the Li nuclei, enabling the acquisition of various data, such as the amount, chemical state and motility of the Li in a sample, regardless of the location, or whether it is a cathode, anode or electrolyte material. Download our LIB app note to find out more.

Natural Products NMR Database

The 13C/1H-NMR database for natural products [CH-NMR-NP] is mainly composed of natural products that were published in major journals in the years between 2000 and the spring of 2014. The total number of compounds is approximately 35,500.

On our corporate dedicated web-page you can access this database.

60 Years of NMR Heritage

In 1956, the first JNM-1 NMR instrument was released by JEOL (at that time, Japan Electron Optics Laboratory Co. Ltd.) and since then, the company has achieved many NMR industry firsts, including:

1972World’s first light pen operation.

1979Superconducting magnet with a resonance frequency of 200 MHz.

1981World’s first full automatic spectrometer.

1985World’s first auto-tuning unit and auto-tune probe, enabling completely remote operation.

2001World’s first spectrometer supporting 10 RF channels.

2013World’s first practical NMR instrument that does not require liquid helium refills.

2017World’s first liquid NMR probe switchable between single tune and dual tune mode without compromising NMR performance.

Today, we take great pride in the long-term stability of our organization and employees who help make JEOL a valuable partner. JEOL customers not only acquire an NMR product that will be of value for many years, they forge a relationship with an organization that will be a lifelong resource for their laboratory, FAB, and business challenges. We are a premier NMR manufacturer and will be proud to be the NMR vendor for your needs. Please also read our published comprehensive history of JEOL NMR.

RIKEN－JEOL Collaboration Center

RIKENRIKEN is Japan's largest comprehensive research institution renowned for high-quality research in a diverse range of scientific disciplines. Founded in 1917 as a private research foundation in Tokyo, RIKEN has grown rapidly in size and scope, today encompassing a network of world-class research centers and institutes across Japan.

Since its establishment in November 2014, the RIKEN-JEOL Collaboration Center has worked on research and development for technologies and applications in the field of Solid State NMR and multi-modal imaging. Since FY2018, it has also addressed the development of advanced cryo-electron microscopy, with the aim of creating new innovations to better compete in the the global marketplace.

The Center is comprised of three units:

  • The Nano-crystallography unit
  • The Multi-Modal Microstructure Analysis Unit
  • The Advanced Electron Microscope Development Unit

This collaboration between JEOL and RIKEN has led to the publication of over 70 papers. JEOL is proud to be on the cutting edge of research and our work with RIKEN is pertinent to these efforts.