Single-Quad Mass Spectrometer

JMS-Q1600GC UltraQuad™ SQ-Zeta

JMS-Q1500GC Single-Quad Mass Spectrometer

The new JMS-Q1600GC UltraQuad™ SQ-Zeta Single Quad Mass Spectrometer of JEOL is our 6th generation high-end Gas Chromatograph Quadrupole Mass Spectrometer (GC-QMS) based on JEOL's 60 years of MS technologies and experience.

From quantitative applications such as environmental samples, water quality control and agrochemicals, to qualitative applications such as materials and aroma analyses, the SQ-Zeta is the ultimate general-purpose GC-MS with high-performance capabilities for a wide variety of measurement and analysis needs.

High sensitivity and Excellent dynamic range

IDL < 5 fg

Eight sequential measurements of 20 fg of octafluoronaphthalene (OFN) were performed by using the standard EI ion source.

The instrument detection limit (IDL) is calculated based on the peak area and reproducibility of the extracted ion chromatogram for the molecular ion. An IDL of 2.6 fg was achieved for the system.

Wide dynamic range

OFN at concentrations ranging from 0.005 to 1,000 pg / uL were measured by using SIM mode with the standard EI ion source. A calibration curve with good linearity was obtained with a coefficient of determination of 0.999 or better. A wide dynamic range of more than 5 orders of magnitude is useful not only for quantitative analysis, but also for qualitative analysis of complex mixtures with different concentrations.

Two Unique EI Ion Sources for Expanded Analytical Solutions

Enhanced Performance Ion Source (EPIS, option) : IDL < 1 fg

The EPIS offers the highest in-class sensitivity in the industry with an instrument detection limit of < 1 fg (OFN 5 fg, eight measurements). As a result, the EPIS offers a variety of benefits that include:

  • Trace-level quantitative analysis
  • Simplification of sample concentration analysis, reduction of sample introduction volume (contamination reduction)
  • Replacement of quantitative measurement method from SIM to SCAN (simplification of measurement condition, non-target analysis possible).
The EPIS can be utilized not only for quantitative analysis but also qualitative analysis.
Eight sequential measurements of 5 fg of octafluoronaphthalene (OFN) were performed by using the EPIS ion source.
The instrument detection limit (IDL) is calculated based on the peak area and reproducibility of the extracted ion chromatogram for the molecular ion. An IDL of 0.6 fg was achieved for the system.

Photoionization EI/PI Combination Ion Source (option)

Photoionization (PI) is a soft ionization method that uses a vacuum ultraviolet (VUV) lamp. The EI/PI combination ion source allows both EI (Hard ionization) and PI (Soft ionization) without removing the ion source. All that is required for switching between EI and PI is to turn OFF the EI filament and turn ON the PI lamp or vice versa.


  • No need to replace the ion source
  • No need to replace the ion source
  • No need for reagent gases
  • Primarily for qualitative analysis
For PI: Lamp: ON, Filament: OFF
For EI: Lamp: OFF, Filament: ON
Schematic of EI/PI Combination Ion Source
Py/GC-MS measurement result of polystyrene foam
Aromatic hydrocarbons, which strongly absorb UV light, are preferentially ionized by PI, resulting in high sensitivity detection of their molecular ions.

Integrated qualitative analysis software "msFineAnalysis iQ"

Break free from qualitative analysis based on library search alone.
A higher level of qualitative analysis is possible by combining EI and soft ionization data.

Based on our highly acclaimed msFineAnalysis software for GC-TOFMS, the new msFineAnalysis iQ expands this integrated qualitative analysis capability into GC-QMS data analysis.
This software automatically combines the library search results from the EI data with molecular ion information from the soft ionization data, and then reports the results in a color coded table. This combination of EI and soft ionization results in improved accuracy for identifying unknowns when compared to relying on library database searches alone.

Work Flow of Integrated Analysis

msFineAnalysis iQ automatically performs the following steps.
  1. Peak detection (deconvolution peak or TIC peak detection)
  2. Link of EI and SI data (link)
  3. Link of EI and SI data (link)
  4. Molecular ion search (SI)
  5. Libray search result (EI, SI integration)Five
  6. Integrated analysis result
Using EI and SI in combination with msFineAnalysis iQ provides a higher level of qualitative analysis results than relying on database searches alone.

Integrated Analysis Result Window

Individual Analysis Window

Key Features

  • Superb ion transmission in the high-mass region prevents ion loss even when introducing high ion currents
  • High performance maintained over a long period of time by combination of a pre-filter, hyperbolic quadrupoles, and a conversion dynode secondary-electron multiplier (SEM).
  • Draw-out lens dramatically reduces chemical noise that hampers high-sensitivity analysis
  • EI (standard), CI, and PI (optional) sources
  • Easy to clean and maintain – ion source can be removed without tools
  • Direct Probes: Direct insertion probe (DIP) and direct exposure probe (DEP)

Application Notes

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