Ultrahigh Sensitivity Autotune Probes using Cryogenic Probe Technology

SuperCOOL Cryogenic Probe

The SuperCOOL probe features significantly improved sensitivity at double the sensitivity of conventional probes and thermal noise is reduced by cooling of both the detection coil and preamplifier. The SuperCOOL probe reduces measurement times to just 1/4 to enable many more samples to be measured in a single day. The SuperCOOL probe accept a 5mm diameter tube, has a wide temperature range from -40°C to +150°C , and also is suitable for polymeric samples of high viscosity.

The SuperCOOL probe (the detection coil is cooled by liquid nitrogen) is highly cost efficient when compared with the UltraCOOL probe (wherein the detection coil is cooled by liquid helium). This probe comes with a new cooling system that does not require a water chiller. As it can run experiments in 1/9 of the time, measurements which used to take several days can now be made in a few hours, thus improving the operational efficiency of the instrument.

Major Features

  • Observable nuclei : 1H; 19F; 31P to 15N
  • Two to three-fold sensitivity improvement for 13C, sensitivity more than doubled for 1H, when compared with a conventional room temperature probe.
  • Wide operational temperature range from -40 to 150°C
  • Auto tuning and matching
  • Field Gradient capability
  • Pre-amplifiers cooled to low temperature for optimum sensitivity gain
  • Operation without consuming coolant for more than one year is possible (circulating type)
  • Liquid nitrogen dewar can be refilled during active data acquisition (open type)
  • Optional ”Probe Lifter”, enabling easy probe change

Measurements at high temperatures of up to 150°C and the high sensitivity of the SuperCOOL probe show outstanding results for polymer samples.

Measurement time is reduced to approx. 1/9 that of a room temperature probe. A 24 hour measurement by a room temperature probe can be done in less than three hours using a SuperCOOL probe.

Comparison of Room Temperature 600MHz to a 500MHz with a SuperCOOL Probe:

The above comparison of a room temperature 600MHz to a 500MHz with a SuperCOOL Probe is done using lasalocid acid. As you can see:

  • The 1st plot is for the 600MHz with a regular RT probe
  • The 2nd plot is for the 500MHz with the SuperCOOL probe
    • The signal to noise ratio is visibly better with the SuperCOOL probe
    • All relevant peaks for lasalocid acid are now clearly visible.

Note: Both data sets were collected under the same conditions for 1024 scans using a 30° pulse at a repetition rate of 2.8s. The large off-scale peaks are from acetone.

UltraCOOL Cryogenic Probe

The UltraCOOL probe achieves more than 4 times the sensitivity of conventional probes while thermal noise is reduced by cooling of both the detection coil and preamplifier. Measurement times using the UltraCOOL probe are only 1/16 that of a conventional probe. What used to be an overnight measurement can now be achieved in a lunch break! The UltraCOOL probe also accepts a 5mm diameter tube, has a wide temperature range from -40°C to +150°C , and is suitable for polymeric samples of high viscosity.

Differences between UltraCOOL probe and SuperCOOL probe

UltraCOOL Probe

Uses cryogenically cooled helium gas to achieve an ultra-low temperature with a recirculating type chiller. The coil/pre-amplifier temperature is much lower than that achieved in the SuperCOOL probe.

SuperCOOL Probe

The SuperCOOL NMR probe is available in 2 configurations:

  • The open cycle design uses liquid nitrogen for cooling to achieve the low coil/pre-amplifier temperature.
  • The closed system version uses cryogenically cooled helium gas to achieve the desired low temperature with a recirculating type chiller.
    • With the circulating type design the coil/pre-amplifier temperature is higher than the UltraCOOL probe.