JEOL USA Press Releases

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   From the journal: Tetrahedron   Abstract During our continuous investigation on a Thai traditional medicinal plant, Stephania venosa Spreng, an alkaloid that seemed to be O-methyldehydrobulbocapnine (MDB) or dehydrocrebanine (DC), had been isolated. However, none of the previously reported 1H- and 13C-NMR data for MDB and DC matched our charts. Thus, we herein report the unambiguous determination of the alkaloid structure as DC via a successful INADEQUATE experiment using 10 mg of the unenriched natural specimen as well as an in silico estimation. Furthermore, ...

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   From the journal: Physical Chemistry Chemical Physics   Abstract Solid-state 13C NMR spectroscopy has been used in conjunction with selectively 13C-labeled mono- and disaccharides to measure 13C–13C spin-couplings (JCC) in crystalline samples. This experimental approach allows direct correlation of JCC values with specific molecular conformations since, in crystalline samples, molecular conformation is essentially static and can be determined by X-ray crystallography. JCC values measured in the solid-state in known molecular conformations can then be compared to corresponding JCC values calculated in the same conformations using ...

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A joint paper was published with the RIKEN-JEOL Collaboration Center, Institute for Integrated Cell-Material Sciences (WPI-iCeMS), University of Warwick, and JEOL RESONANCE Inc. This article has also been featured on the cover! Highlights: Selective detection of 1H signals of API in a tablet formulation is proposed. 1H signals of excipients are suppressed. 1H signals in the vicinity of nuclei (here 14N) which only appear in API are excited. 1H{14N} magnetization is diffused to 1Hs in API crystals by RFDR recoupling.   Link to the ...

2 March 2020, PEABODY, MA:  JEOL USA, a leader in developing instruments used to advance scientific research and technology, is pleased to highlight its latest key strategic partnerships at Pittcon 2020: Mass-Spectrometry: NETZSCH integrated Thermal Analysis GC/MS system Electron Microscopy: Acquisition of Integrated Dynamic Electron Solutions, Inc. NMR Spectroscopy: RIKEN-JEOL Collaboration Center and the Kyoto University Bob Pohorenec, JEOL USA’s President commented: “JEOL is committed to developing cutting edge technologies to help scientists to answer ever-complex questions. Our ...

2 March 2020, PEABODY, MA:  JEOL USA, a leader in developing instruments used to advance scientific research and technology, is pleased to showcase the latest updates to its core product range at Pittcon 2020.  JEOL has 70 years of expertise in the field of electron microscopy, more than 60 years in mass spectrometry and NMR spectrometry, and more than 50 years of e-beam lithography leadership. Mass spectrometry (MS) JEOL expanded its mass spectrometer product line with the development ...

Elucidating novel crystalline structures with electron and NMR crystallography Author(s): Dr. Michael Frey, Analytical Instruments Product Manager, JEOL USA, Inc and Dr. Yusuke Nishiyama, Research Scientist, JEOL RESONANCE Inc Determining the crystal structure of chemical compounds and biological molecules, by defining the precise spatial arrangements of their atoms in a crystalline state, is crucial to understanding their function and reactivity. In addition to crystalline structure, analyzing the hydrogen bonding strength between hydrogen and electronegative atoms is ...

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11 JUNE 2019, PEABODY, MA: JEOL USA has announced the addition of two new products to its nuclear magnetic resonance (NMR) portfolio. The  2mm Magic Angle Spinning (MAS) NMR Probe for Solids and Pre-Heat Auto-Sample Changer (ASC) expand JEOL’s extensive offering of advanced NMR solutions for polymer research, materials science and biosolids. The 2mm MAS NMR Probe is well suited for both materials and biosolids NMR. The 2mm MAS Probe is the ideal compromise in ...

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PEABODY, MA:17 January 2019: JEOL USA has developed new methodology using the company’s ROYAL HFX Probe to offer a powerful and practical alternative for the elucidation of crucial structural information. It has particular merit in the analysis of complex pharmaceutical mixtures that contain a drug substance plus its various metabolites.  It’s a familiar challenge for pharmaceutical development scientists and now, rather than relying on chromatography to separate a mixture ahead of the analysis of selected ...

(November 8, 2018, Peabody, Mass.) --  JEOL has achieved a major expansion in the quantitative and statistical analysis capability of its Nuclear Magnetic Resonance Spectrometers (NMR) through collaboration with the developer of the revolutionary CRAFT (Complete Reduction to Amplitude-Frequency Table) data processing technique.   In conjunction with the recent JEOL DELTA NMR software release 5.3.0, CRAFT for DELTA V1.0 provides direct time domain-to-spreadsheet analysis, allowing for more objective extraction of quantitative information for compounds of interest, ...

October 11, 2018 (Peabody, MA) -- JEOL announces that it has been awarded a major contract by the US DEA Office of Forensic Sciences for nine JEOL JNM-ECZ500R Nuclear Magnetic Resonance (500 MHz NMR) spectrometers.  The purchase was made through a competitive award process and will allow DEA laboratories across the country to utilize the latest NMR technology to combat the proliferation of new and existing illicit drugs.  The contract allows for replacement of ...