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COSY/TOCSY Analysis│Interpreting spin correlations using 2D NMR

In this article, we explain the basic principles and analysis methods of COSY and TOCSY, which are representative techniques of 2D NMR. Starting from confirming correlations between adjacent protons using COSY, we introduce spin network analysis with TOCSY and analysis of carbohydrate using 1D and 2D TOCSY, with concrete examples.

Basics of NOE/NOESY: Causes and Solutions When NOE Is Not Detected

NOE (Nuclear Overhauser Effect) is an important NMR measurement technique that can reveal spatial proximity relationships within molecules. In this column, we discuss the difference between difference NOE, 1D NOESY, and 2D NOESY, and how to select each method, the relaxation time that is key for analysis. The causes and solutions for cases when NOE is not detected are also covered. Moreover, we answer the frequently asked questions and explain the key points for effective use of NOE measurement.

Structural Analysis of Organic Compound Using 2D - NMR Spectrum

In this article, we will explain the structural analysis of organic compound by using 2D-NMR spectrum.

How to read NMR spectra from the basics (chemical shift, integration ratio, coupling)

This article provides easy-to-understand explanations about what we can learn from the NMR spectra (chemical shift, integration ratio, and coupling)

Structural biology 101: Principles, techniques and applications

Our article on structural biology 101 will help you familiarize yourself with its principles, techniques and applications. Click here to get started!

NMR Analysis of Lithium Ion Batteries

The search for new battery materials, alongside the drive to improve performance, and lower the cost of existing and new batteries, comes with its challenges.