A study of dioxins analysis by GC/MS/MS with hydrogen carrier gas
MSTips No. 507
Introduction
Dioxins are primarily analyzed by using a gas chromatograph/double-focusing magnetic sector high-resolution mass spectrometer (GC/HRMS) [1, 2]. Recently, however, the EU and China have recognized the use of GC-tandem mass spectrometer (GC/MS/MS) for the analysis of dioxins in food and feed [3, 4]. GC/MS/MS is also being considered by the EPA for measurement. Against this background, Japan is exploring the use of GC/MS or GC/MS/MS as alternatives to GC/HRMS, and we have also reported the results of dioxins analysis by GC/MS/MS [5, 6]. Recently, the dioxins analysis has been also conducted using alternative carrier gases that is similar to water quality analysis and pesticide analysis. However, the number of reports of this analysis is very small compared to that of water quality analysis and pesticide analysis. In this study, we report a comparative analysis of dioxin analysis by hydrogen carrier gas with helium carrier gas using GC/MS/MS “JMS-TQ4000GC UltraQuad™ TQ” (Figure 1).