MALDI-TOFMS imaging system JEOL×SCiLS Advanced statistical analysis of MALDI MS imaging data acquired by SpiralTOF™-plus while taking full advantage of its high mass-resolving power June 10, 2021 Application Note, MALDI Imaging, Mass Spectrometry (MS), Product Brochures (MS) 0 Comment Read More >>
MALDI imaging brochure Advanced statistical analysis of MALDI MS imaging data required by SpiralTOF-plus while taking full advantage of its high mass-resolving power. March 19, 2021 Application Note, MALDI Imaging, Mass Spectrometry (MS), Product Brochures (MS), SpiralTOF™ 0 Comment Read More >>
SpiralTOF Imaging Applications Notebook 2020 Applications concerning MALDI MS Imaging using the SpiralTOF. March 11, 2021 Application Note, MALDI Imaging, Mass Spectrometry (MS) 0 Comment Read More >>
Degradation of PET by UV irradiation using S3000 - MSTips 307 In this report, we have applied this combined method to analyze a polyethylene terephthalate (PET) that was degraded by ultraviolet (UV) irradiation. June 22, 2020 Application Note, MALDI Imaging, Mass Spectrometry (MS), SpiralTOF™-TOF 0 Comment Read More >>
Degradation analysis of PET film by UV irradiation using MALDI-MSI & FE-SEM-HS05 In this report, we have expanded MALDI-MSI to analyzing a PET film that was exposed to UV radiation. Additionally, a SEM was used to look at the morphological differences in the PET film before and after UV irradiation. June 22, 2020 Application Note, MALDI Imaging, Mass Spectrometry (MS), SpiralTOF™-TOF, Yokogushi (Cross-platform Analysis) 0 Comment Read More >>
MS imaging for visualizing synthetic polymers using average MW and p as indices - MSTips 305 In this report, we investigate a MSI visualization method for synthetic polymers that uses Mn, Mw and D as indices for visualization. June 12, 2020 Application Note, MALDI Imaging, Mass Spectrometry (MS), SpiralTOF™ 0 Comment Read More >>
MS imaging for visualizing synthetic polymers combined with KMD - MSTips - 306 In this report, we have combined this method with the Kendrick Mass Defect (KMD) method to effectively visualize polymer series mixtures. June 12, 2020 Application Note, MALDI Imaging, Mass Spectrometry (MS), SpiralTOF™ 0 Comment Read More >>
Tissue imaging with high mass-resolving power and high-energy CID The JMS-S3000 is based on JEOL's proprietary SpiralTOF ion optic system that offers the highest resolving power available in a MALDI-TOF mass spectrometer. The unique properties of the SpiralTOF provide a new level of performance in MALDI imaging. March 5, 2020 Application Note, MALDI Imaging, Mass Spectrometry (MS) 0 Comment Read More >>
Mass Spectrometry Imaging (MSI) on mixed conductive/non-conductive substrate using JMS-S3000 SpiralTOF™ - MSTips - 288 In the industrial field, there is interest in measuring organic compounds on non-conductive substrates, such as resins a few millimeters thick. If the mass spectrum is obtained from the non-conductive surface with no pre-treatment, the mass resolution will be lower, and ultimately the ion intensity will decrease significantly due to the charge-up effect. This issue can be solved by providing conductivity to the non-conductive part via the gold deposition method.[1] In this report, MSI is performed using a permanent red marker on a substrate with a conductive part and a non-conductive part. Previously, ions could be observed only from the conductive part. Now, with the gold deposition method, they can be observed from both the conductive and the non-conductive parts, and they can be properly mapped. March 5, 2020 Application Note, MALDI Imaging, Mass Spectrometry (MS) 0 Comment Read More >>
MALDI-Imaging MS of Lipids on Mouse Brain Tissue Sections Using Negative Ion Mode The main biological functions of lipids include energy storage, signaling, and acting as structural components of cell membranes. Not only their chemical composition and structures but also the distributions in biological body are important for biochemistry. Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-Imaging MS) is a powerful tool for the biochemical analyses of surfaces. Different lipid types are observed in positive or negative-ion MALDI mass spectra, depending on the presence of polar functional groups. Phosphatidyl cholines and galactosyl ceramides were mainly observed in the MALDI-Imaging MS of positive ion mode using JMS-S3000 SpiralTOF[1]. In this work, we report the use of the SpiralTOF for negative-ion MALDI-Imaging MS of sulfatides. High-resolution, accurate mass data and MS/MS data obtained under high-energy CID conditions provide information about structures, elemental compositions, and localization of many types of sulfatides. March 5, 2020 Application Note, MALDI Imaging, Mass Spectrometry (MS) 0 Comment Read More >>