Checking the isotopic composition of a labeled peptide by using inlet ionization with the Ambient Ionization Toolbox™
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- 1 MIN READ |
- 19 |
- July 29, 2026 |
- Mass Spectrometry (MS) |
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The AccuTOF-DART Ambient Ionization Toolbox™ provides a variety of ambient ionization methods for rapid and convenient analysis of diverse compound types. Here, an isotopically labeled peptide was purchased from a vendor at a suspiciously low price. Inlet ionization with 3-nitrobenzonitrile matrix revealed that the sample did not contain the expected 13C and 15N labels. A separate sample of the isotopically labeled peptide from an alternate supplier showed the expected labeling.