Analytical Instrument Documents

In this application note, the EO/PO composition ratio using MALDI-TOFMS were investigated for the EO-PO copolymers with six different molecular weight distributions and EO/PO compositions.

The Kendrick Mass Defect (KMD) method has made it possible to easily visualize polymer series contained in complex high mass-resolution mass spectra. Here, we introduce examples of analyzing a mixture of two types of binary polyesters and a quaternary polyester.

In this report, we performed an end-group analysis of polymer samples with a high polydispersity and molecular weight of less than 50,000 by combining SEC and high-performance MALDI-TOFMS. In particular, we report on (i) improvement of the efficiency of fractionation by SEC and pretreatment for MALDI-TOFMS measurement, (ii) improvement of visualization of end group changes in mass spectra of SEC fractionated samples with reduced polydispersity, (iii) End group analysis in the high molecular weight region (molecular weight 10,000 to 20,000).

Using a Poropare™, we investigated MSI measurement of components inside strawberries, which are generally challenging to make tissue sections for mass imaging. Although the transfer plate has a large uneven structure due to the transfer function, it was found that by combining it with the SpiralTOF™-plus3.0, which has a long flight distance, mass imaging with high resolution and high mass accuracy is possible even in the low molecular weight region.

In this study, we investigated the visualization of information obtained from high-resolution MALDI-TOFMS measurements of polymer fractions collected via reversed-phase LC, using Kendrick Mass Defect (KMD) plots. The analysis focused on the following two aspects: (1) Comparison of KMD plots before and after fractionation, and (2) Effect of different fractionation intervals (30 second / 15 second) on the visualization in KMD plots.

In this application note, labeled N‑linked glycans (Fig. 1) were analyzed using the JMS‑S3000, and results of accurate mass measurements in the SpiralTOF mode and structural analysis in the TOF‑TOF mode are presented.

In this application note, dipeptides extracted from natto were analyzed. The results of amino acid composition analysis using the SpiralTOF mode and structural analysis using the TOF‑TOF mode are reported.

Pyrolysis‑GC‑MS provides structural information on substructures originating from monomers and end groups. While many detected pyrolysis products are not registered in the NIST library, automated analysis be achieved using AI structure analysis with msFineAnalysis AI.

In this report, we attempt to improve the image quality of extracted mass images using the FINE-AI Filter, which was developed by applying a machine-learning model for noise filtering—originally created from secondary electron images obtained by scanning electron microscopy (SEM)—to MALDI-MSI.

In this report, we attempted end group analysis using high-precision MALDI-TOFMS after SEC fractionation of polycarbonate (PC) with high polydispersity.