Related Articles

• Analyzing a Specific Component using Group Analysis of msFineAnalysis Ver. 2 - MSTips 303

  In 2018, we announced the msFineAnalysis software which was designed to automatically integrate two types of data acquired by EI and soft ionization. Recently, we developed msFineAnalysis Version 2, an enhanced version with additional features. msFineAnalysis Version 2 incorporates two new features: Chromatographic Deconvolution and Group Analysis. In this work, we use the group analysis capabilities of the software to evaluate the pyrolysis GC-MS results for a vinyl acetate resin.
• Integrated Analysis of an Acrylic Resin using msFineAnalysis v2 - MSTips 300

  In 2018, msFineAnalysis Ver.1 software was released in which data acquired by EI, soft ionization, and accurate mass measurements were automatically integrated to generate a qualitative report for samples measured by these techniques with GC-MS. Recently, msFineAnalysis Ver.2 was introduced as an enhanced version with additional features. In this work, we will describe the changes in Ver.2, which now includes chromatographic deconvolution, and present applications using the new features.
• Integrated Analysis of Fatty Acid Methyl Esters using msFineAnalysis v2 - MSTips 301

  Fatty acid methyl esters (FAMEs) are crucial for determining the fat content in food. Being environmentally friendly, they are also increasingly used as bio-diesel fuels. Many of the FAMEs are unsaturated with double bonds in the alkyl chains. As the number of double bonds increases (more unsaturation), the EI measurements tend to lack molecular ions. In this work, we measured a standard sample containing multiple FAMEs using EI and FI to detect their molecular ions. The resulting data was further examined by using msFineAnalysis to produce an integrated report for these compounds in which the library database search was combined with the molecular ion exact mass analysis to produce a qualitative identification of these compounds.
• Analysis of organic compounds on an acrylic plate using JMS-S3000 SpiralTOF™ - MSTips - 251

  Industrial materials are often evaluated by surface analysis instruments that provide information on surface elements, bonding states, and functional groups. However, there are limited options for surface analysis techniques that provide molecular weight and molecular structure information for organic compounds present on surfaces. Matrix Assisted Laser Desorption Ionization - Time of Flight Mass Spectrometry (MALDI-TOFMS) is a soft ionization technique that can be used to analyze surfaces in order to estimate elemental compositions with accurate mass measurements, obtain structural information by using MS/MS, and map surface compounds by using MS imaging. MALDI-TOFMS uses a high voltage on the target plate to accelerate the ions into the TOFMS analyzer. Therefore, the target plates are conductive and are typically made of stainless steel. MALDI imaging mass spectrometry is widely used for analyzing organic substances on frozen tissue sections. In this case, a frozen tissue section with a thickness of about 10 μm is placed on a conductive glass slide coated with an indium tin oxide (ITO) film. However, for the analysis of industrial products, the target organic compounds are on nonconductive substrates such as resins with millimeter thicknesses. MALDI-TOFMS surface measurements using nonconductive substrates lead to a reduction in mass resolution and a significant decrease in ion intensity due to surface charging. This problem can be solved by pretreating the surface with gold vapor deposition in order to change it from nonconductive to conductive. This method was previously shown to work well in MSTips No. 204 in which the gold vapor deposition method was applied to the MALDI-MS imaging analysis of inks on paper. In this report, we used gold vapor deposition to look at samples on the surface of a 1 mm thick acrylic plate.
• Analysis of organic compounds on an acrylic plate using JMS-S3000 "SpiralTOF"

  Industrial materials are often evaluated by surface analysis instruments that provide information on surface elements, bonding states, and functional groups. However, there are limited options for surface analysis techniques that provide molecular weight and molecular structure information for organic compounds present on surfaces. Matrix Assisted Laser Desorption Ionization - Time of Flight Mass Spectrometry (MALDI-TOFMS) is a soft ionization technique that can be used to analyze surfaces in order to estimate elemental compositions with accurate mass measurements, obtain structural information by using MS/MS, and map surface compounds by using MS imaging. MALDI-TOFMS uses a high voltage on the target plate to accelerate the ions into the TOFMS analyzer. Therefore, the target plates are conductive and are typically made of stainless steel. MALDI imaging mass spectrometry is widely used for analyzing organic substances on frozen tissue sections. In this case, a frozen tissue section with a thickness of about 10 μm is placed on a conductive glass slide coated with an indium tin oxide (ITO) film. However, for the analysis of industrial products, the target organic compounds are on nonconductive substrates such as resins with millimeter thicknesses. MALDI-TOFMS surface measurements using nonconductive substrates lead to a reduction in mass resolution and a significant decrease in ion intensity due to surface charging. This problem can be solved by pretreating the surface with gold vapor deposition in order to change it from nonconductive to conductive. This method was previously shown to work well in MSTips No. 204 in which the gold vapor deposition method was applied to the MALDI-MS imaging analysis of inks on paper. In this report, we used gold vapor deposition to look at samples on the surface of a 1 mm thick acrylic plate.
• Analysis of organic compounds on an acrylic plate using JMS-S3000 "SpiralTOFTM"

  Industrial materials are often evaluated by surface analysis instruments that provide information on surface elements, bonding states, and functional groups. However, there are limited options for surface analysis techniques that provide molecular weight and molecular structure information for organic compounds present on surfaces. Matrix Assisted Laser Desorption Ionization - Time of Flight Mass Spectrometry (MALDI-TOFMS) is a soft ionization technique that can be used to analyze surfaces in order to estimate elemental compositions with accurate mass measurements, obtain structural information by using MS/MS, and map surface compounds by using MS imaging. MALDI-TOFMS uses a high voltage on the target plate to accelerate the ions into the TOFMS analyzer. Therefore, the target plates are conductive and are typically made of stainless steel. MALDI imaging mass spectrometry is widely used for analyzing organic substances on frozen tissue sections. In this case, a frozen tissue section with a thickness of about 10 μm is placed on a conductive glass slide coated with an indium tin oxide (ITO) film. However, for the analysis of industrial products, the target organic compounds are on nonconductive substrates such as resins with millimeter thicknesses. MALDI-TOFMS surface measurements using nonconductive substrates lead to a reduction in mass resolution and a significant decrease in ion intensity due to surface charging. This problem can be solved by pretreating the surface with gold vapor deposition in order to change it from nonconductive to conductive. This method was previously shown to work well in MSTips No. 204 in which the gold vapor deposition method was applied to the MALDI-MS imaging analysis of inks on paper. In this report, we used gold vapor deposition to look at samples on the surface of a 1 mm thick acrylic plate.