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JMS-S3000 SpiralTOF™ series Life Science Applications Notebook
JMS-S3000 SpiralTOF™ series Life Science Applications Notebook

Edition May 2026

Table of Contents

Mass Spectrometry Imaging P1〜

  • Phase analysis of mass spectrometry imaging data using high-resolution MALDI-TOFMS “NewSpiralTOF™” and vertex component analysis (MSTips No. 528)
  • Mass image quality improvement using a machine learning model “FINE-AI Filter” (MSTips No. 526)
  • Mass imaging of strawberry using the JMS-S3000 “SpiralTOF™-plus3.0” and transfer plate Poropare™ (MSTips No. 499)
  • High Mass-Resolution MALDI-imaging MS for Drug Metabolism in Tissue Using the JMS-S3000 (MSTips No. 212)
  • High Mass Resolution MALDI-imaging MS Using JMS-S3000 SpiralTOF™ and msMicroImager (MSTips No. 211)
  • Fingerprint Analyses Using MALDI Imaging and SEM Imaging (MSTips No. 208)
  • MALDI-Imaging MS of Lipids on Mouse Brain Tissue Sections Using Negative Ion Mode (MSTips No. 196)

Proteins and Peptides P23〜

  • High-Resolution Measurements of Proteins Using the Spiral Mode of JMS-S3000 “SpiralTOF™” (MSTips No. 297)
  • MALDI-ISD Measurements Using Both the SpiralTOF™ Mode and the Linear Mode (MSTips No. 229)
  • High Resolution and High Mass Accuracy MALDI-ISD Measurements (MSTips No. 228)
  • High Sensitivity Analysis of Intact Proteins Using Linear TOF (MSTips No. 227)
  • High Sensitivity Peptide Measurement with the New Matrix α-Cyano-4-Chlorocinnamic Acid
  • Distinguishing Lysine and Glutamine in a Peptide
  • Analysis of Phosphopeptide Using TOF-TOF (MSTips No. 184)
  • Comparison of the JMS-S3000 SpiralTOF™-TOF and a 4-Sector Tandem Double-Focusing Mass Spectrometer (MSTips No. 181)
  • Structural Analysis of a High Molecular Weight Peptide (MSTips No. 175)
  • High-Energy CID Analysis of Bovine Serum Albumin (MSTips No. 174)
  • Analysis of Bovine Serum Albumin (MSTips No. 166)

Lipids P51〜

  • Structural Analysis of Oxidized Triolein (MSTips No. 197)
  • Structural analysis of phospholipids in egg yolk using JMS-S3000 “SpiralTOF™” with TOF-TOF option (MSTips No. 185)
  • Structural Analysis of Triolein (MSTips No. 182)
  • Structural Analysis of Tristearin (MSTips No. 178)
  • Aglycon diversity of brain sterylglucosides: structure determination of cholesteryl- and sitosterylglucoside (Akiyama, H., et al., J. Lipid Res. 57, 2061-2072, 2016; open access article under the CC BY license)
  • Structural Analysis of Triacylglycerols by Using a MALDI-TOF/TOF System with Monoisotopic Precursor Selection (Kubo, A., et al., J. Am. Soc. Mass Spectrom., 24, 684-689, 2013; open access article ©The Authors, 2012)

Oligosaccharides P77〜

  • Compositional and Structural Analysis of Labeled N-Linked Glycans Using JMS-S3000 NewSpiralTOF™ (MSTips No. 519)
  • High-energy CID Mass Spectrometry of Oligosaccharides (MSTips No. 366)

Nucleic Acids P83〜

  • Analysis of oligonucleotides using JMS-S3000 "SpiralTOF™-plus 2.0" (MSTips No. 364)

Natural Products P85〜

  • Molecular Structure Analysis of Alkaloids (ED2022-05E)
  • Analysis of the Natural Organic Compound SAAF by Using the TOF-TOF Option (MSTips No. 183)
  • Analysis of the Natural Organic Compound YTX by Using the TOF-TOF Option

Drugs / Small Molecules P91〜

  • Amino Acid Composition and Structural Analysis of Dipeptides in Natto Using JMS-S3000 NewSpiralTOF™ (MSTips No. 521)
  • Structural analysis of a small molecule using JMS-S3000 "SpiralTOF™-plus 2.0" ー MS/MS measurement of a photodegradation product of reserpine ー (MSTips No. 365)
  • Analysis of a drug in urine by JMS-S3000 "SpiralTOF™" and TOF-TOF option (MSTips No. 263)
  • Structural analysis of melatonin and related compounds using JMS-S3000 SpiralTOF™ with the TOF-TOF option (MSTips No. 256)
  • Analysis of medicinal properties in a combination cold remedy by using JMS-S3000 “SpiralTOF™” (MSTips No. 241)
  • High-Energy CID MS-MS Analysis of Small Organic Molecules (MSTips No. 173)
  • MALDI for Small Molecule Analysis: A Complex Drug Mixture
  • Accurate mass measurement of small organic molecules using JMS-S3000 “SpiralTOF™” (MSTips No. 168)

Details of the hardware and software P111〜

  • Mass Spectrometry Imaging using the JMS-S3000 “SpiralTOF™-plus” Matrix Assisted Laser Desorption Ionization Time-of-Flight Mass Spectrometer (Takaya Satoh, JEOL News, 55, 70-72, 2020)
  • Development of JMS-S3000: MALDI-TOF/TOF Utilizing a Spiral Ion Trajectory (Takaya Satoh, JEOL News, 45, 34-37, 2010)
  • The Relationship between Crystal Condition and Mass Resolving Power, Mass Accuracy (MSTips No. 206)
  • High Mass Resolution MALDI-Imaging MS – High Stability of Peak Position during Imaging MS Measurement (MSTips No. 193)
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