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msFineAnalysis iQ Ver.2 Target Analysis Example Ⅳ Analysis of Aroma Compounds in “Hojicha” using Thermal Desorption GC-MS and Exploration of Pyrazines
msFineAnalysis iQ Ver.2 Target Analysis Example Ⅳ Analysis of Aroma Compounds in “Hojicha” using Thermal Desorption GC-MS and Exploration of Pyrazines
MSTips No. 506

Introduction

Pyrazines are known as key aroma compounds that characterize the roasted aroma of Hojicha, and in recent years, they have attracted attention for their potential health benefits. Thermal desorption (TD)-GC-MS is an analytical method used for analyzing food aroma components. Although the method enables highly sensitive and comprehensive analysis of aroma compounds in samples, searching for specific target compounds among the many detected components can be time-consuming.
Target Analysis function on the msFineAnalysis iQ is a method for fast and accurate search and evaluation of only the target compounds based on integrated qualitative analysis1) with EI and Soft Ionization (SI) data. In this method, it is necessary to register the CAS RN® and/or molecular formula (or molecular weight), fragment composition formula of target compounds in the “Target List” in advance. Based on the registered information, each extracted ion chromatogram (EIC) is plotted for EI and SI measurement data and peaks are detected. The molecular ion peak in the mass spectrum, its isotopic pattern, similarity and retention index with the NIST database are confirmed about the detected peak to determine whether it is the target compound. This time, we analyzed the aroma components of Hojicha using the TD-GC-MS and rapidly identified only pyrazines through Target Analysis.

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