Analytical Instrument Documents

In this report, we analyzed the oligomer region of the same samples using a high-resolution MALDI-TOFMS JMS-S3000 "SpiralTOF™-plus 2.0" in combination with Kendrick Mass Defect (KMD) analysis.

In this report, we performed structural analysis of the end groups of poly(methyl methacrylate) by using MALDI-TOFMS and pyrolysis GC-TOFMS in a complementary manner.

In MSTips No. 333, we reported the measurement results of anionic surfactants less than m/z 1000. In this application note, we report the measurement of polyethylene glycol (average molecular weight 5000) having phosphate groups as an end group.

Here, we will report on the binary copolymer search function newly added to msRepeatFinder V6 and the resulting compositional analysis of EO-PO copolymers using the degree of polymerization plot.

In this report, we report the statistical analysis of high-mass resolution MALDI-MSI data of various lipids in biological samples.

SpiralTOF™-plus 2.0 with TOF-TOF option can achieve high precursor ion selectivity due to the long flight path of the spiral ion optics used in the 1st TOFMS. In this application note, we report the structural elucidation of a photodegradation product of reserpine as an example of structural analysis of a component close to a possible interference in mass by MS/MS measurement using the SpiralTOF™-plus 2.0 with TOF-TOF option.

Molecular weight confirmation of synthesized oligonucleotides is important for the quality control of pharmaceuticals. In this report, we used the synthesized oligonucleotide (Table 1) as a sample and measured it with a MALDI-TOFMS.

Recently, it has been possible to efficiently overview the information in the mass spectra of complex polymer mixtures using a Kendrick Mass Defect (KMD) analysis software, msRepeatFinder. Determining the elemental composition of the end groups of the polymer series identified in this way is essential for confirming the state of polymer synthesis reactions, quality control of products, and analysis of degradation mechanisms. In this report, we introduce the procedure for determining the elemental compositions of the end groups from the accurate mass information of the polymer.

The AES was observed as RO-(EO)n-SO3Na+Na+ in the positive ion mode. If the sample containing AES and POEAE, the mass spectrum will be complicated because both of them can be ionized in the positive ion mode. On the other hand, AES was selectively ionized in the negative ion mode. Furthermore, end-groups were estimated by TOF-TOF negative ion mode. It was found that if an anionic surfactant such as AES is contained in the sample, it is worth trying to confirm their existence and perform structural analysis using negative ion mode.

In this work, we used Py-GC-QMS and high-resolution MALDI-TOFMS to evaluate the effects of UV irradiation on polystyrene (PS).