Direct Analysis in Real-Time


The AccuTOF™-DART® 4G is an atmospheric pressure ionization, high-resolution time-of-flight mass spectrometer (API-HRTOFMS). This robust and versatile mass spectrometer provides solutions for a wide variety of fields with interchangeable atmospheric and ambient ionization sources. The AccuTOF-DART 4G will exponentially improve your MS workflow - it is the only high-performance mass spectrometer system that works as fast as you think!


Direct Analysis in Real Time DART - A Powerful Problem-solving Tool

The AccuTOF-DART 4G allows you to immediately determine chemical composition and produce high-resolution, accurate mass spectra by simply placing a sample in its native form between the DART ion source and the AccuTOF mass spectrometer inlet. The DART source ionizes almost anything you put in front of it including solutions straight from your synthetic reaction pot, crude extracts, unknown pills or powders, polymers and adhesives, contamination on small parts, sticky liquids, vapors, TLC plates, and more. Many analyses can be carried out with little or no sample preparation.

The AccuTOF Advantage

The AccuTOF-DART is the perfect union of advanced time-of-flight mass spectrometer with the open air ion source that completely changed the field of mass spectrometry. Developed on the AccuTOF here at JEOL, the DART ion source is fully integrated with the mass spectrometer. No additional pumps, flanges, or interface hardware are required. This makes it possible to carry out unique ambient ionization experiments that are not practical on other mass spectrometers and produces clean, reproducible, easy-to-interpret data.

The third-generation AccuTOF-DART 4G system is an “ambient ionization toolbox” that allows the analyst to choose ionization methods that are best matched to the samples to be analyzed. The DART ion source can be operated on the AccuTOF-DART 4G in several different modes, plus a wide range of ambient ionization methods can be carried out without removing the DART ion source.

The Ambient Ionization Toolbox - list of applications

* PaperSpray® is a registered trademark of the Purdue Research Foundation and is used under license.

AccuTOF-DART Evolution

The Direct Analysis in Real Time (DART) ion source was developed on the JEOL AccuTOF mass spectrometer as the first ambient ion source and the AccuTOF-DART™ was introduced in 2005 as the first commercially available ambient ionization mass spectrometer.

AccuTOF™ DART® Details

  • Wide Analytical Range
  • Real Time Analysis
  • Polar and non-polar compounds
  • No interface between DART and the mass spectrometer
  • Powerful problem solving tool with unlimited applications
  • Award-winning technology
  • Widely used in forensics, troubleshooting, material analysis, environmental testing, support for synthetic chemistry, and much more.


Drug Analysis

Food, Flavors, Fragrances


Homeland Security

Industrial Materials

Organic Synthesis



DART Applications Notebook 2016

AccuTOF-DART 4G Brochure: Measure Accurate-mass Mass Spectrum of NMR Sample Solution with No Preparation

Read the comprehensive article: Direct Analysis in Real Time (DART) Mass Spectrometry

Learn how easy it is to apply AccuTOF DART technology to a wide variety of chemical and forensic problems: This fourth edition contains all of our AccuTOF DART Application Notes.

Pittcon 2013 Talk: New and Emerging Analytical Technologies in Forensic Science

Interview: Versatile and powerful tool for forensic drug screening

REALab Customer Story: State University of New York (Albany)

AccuTOF-DART presented by Bob Steiner, Drug Chemist at Virginia Department of Forensic Science and Affiliate Assistant Research Professor at Virginia Commonwealth University

For Your Lab

28 JUN

DART Infographic.jpg


Dart Infographic

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DART Awards

DART wins Pittcon 2005 Gold
DART® wins Pittcon® 2005 Editors' Gold Award for Best New Product

DART wins R&D 100 Award
DART® wins R&D 100 Award