Direct Analysis of Adhesives March 4, 2020 4. Forensics, 6. Industrial Materials, AccuTOF™ DART®, Application Note, Mass Spectrometry (MS) 0 DART can be used with a heated gas stream to rapidly pyrolyze and identify low-volatility materials such as adhesives and resins, directly on surfaces. Although these materials are not pure compounds, a library of DART mass spectra can be created and searched to identify materials, and exact mass measurements coupled with accurate isotopic abundances can be used to identify unknown components. Examples are shown here for cured and uncured epoxies and acrylate adhesives on metal and glass. All samples were analyzed by acquiring positive-ion mass spectra with the DART source operated with helium and a gas heater setting of 450° C (helium temperature ~350° C). All mass spectra were measured over the m/z range 60-1000 at a resolving power of 6000. Following each analysis, a glass rod coated with PEG 600 was placed in front of the DART source to provide a calibration for exact mass measurements. A nominal mass library of adhesive mass spectra was created by using the software link to the NIST version 2.0 mass spectra database search program. All figures shown here are copied from that library and only integer masses are shown although exact masses were recorded for all peaks. For full details: Attached files often contain the full content of the item you are viewing. Be sure and view any attachments. Adhesives.pdf 67.69 KB Related Articles Analyzing a Specific Component using Group Analysis of msFineAnalysis Ver. 2 - MSTips 303 In 2018, we announced the msFineAnalysis software which was designed to automatically integrate two types of data acquired by EI and soft ionization. Recently, we developed msFineAnalysis Version 2, an enhanced version with additional features. msFineAnalysis Version 2 incorporates two new features: Chromatographic Deconvolution and Group Analysis. In this work, we use the group analysis capabilities of the software to evaluate the pyrolysis GC-MS results for a vinyl acetate resin. Integrated Analysis of an Acrylic Resin using msFineAnalysis v2 - MSTips 300 In 2018, msFineAnalysis Ver.1 software was released in which data acquired by EI, soft ionization, and accurate mass measurements were automatically integrated to generate a qualitative report for samples measured by these techniques with GC-MS. Recently, msFineAnalysis Ver.2 was introduced as an enhanced version with additional features. In this work, we will describe the changes in Ver.2, which now includes chromatographic deconvolution, and present applications using the new features. Direct analysis in real time mass spectrometry with collision-induced dissociation for structural analysis of synthetic cannabinoids DART-MS spectra were acquired under CID conditions to rapidly differentiate among five synthetic cannabinoids contained within ’herbal’ products purchased locally in New York State (USA). The spectra exhibited [M+H]+ ions and product ions unique to each cannabinoid that corresponded to major structural features. Five different cannabinoid analogs, alone and as mixtures of at least two cannabinoids, were identified in six herbal products and differentiated by their CID product ion patterns. Integrated Analysis of Fatty Acid Methyl Esters using msFineAnalysis v2 - MSTips 301 Fatty acid methyl esters (FAMEs) are crucial for determining the fat content in food. Being environmentally friendly, they are also increasingly used as bio-diesel fuels. Many of the FAMEs are unsaturated with double bonds in the alkyl chains. As the number of double bonds increases (more unsaturation), the EI measurements tend to lack molecular ions. In this work, we measured a standard sample containing multiple FAMEs using EI and FI to detect their molecular ions. The resulting data was further examined by using msFineAnalysis to produce an integrated report for these compounds in which the library database search was combined with the molecular ion exact mass analysis to produce a qualitative identification of these compounds. Comprehensive Analysis + Unknown Component Analysis of Vinyl Acetate Resins Using Pyrolysis GC-MS Advances in mass spectrometry are enabling analysis of micro samples and unknown components that were not observable before. As the volume of information acquired from mass spectrometry increases, researchers are calling for simple techniques to analyze numerous components observed, and as a result, there is a rise in demand for comprehensive analytical techniques including multiple classification analysis. In this work, we will introduce a new technique for non-target analysis, which combines comprehensive analysis using high resolution GC-TOFMS and unknown component analysis using soft ionization. Direct, Real-Time Mass Spectrometry Analysis of Cinnamon To ensure food safety, rapid detection of adulterated and counterfeit food products is critical. One such method, Direct Analysis in Real Time-Mass Spectrometry (DART-MS) (IonSense, Saugus, Mass.), quickly screens and analyzes a wide array of samples for mass spectral information and does not require sample preparation. As an example, several recent studies detail the analysis of cinnamon, mostly using chromatographic methods. High concentrations of coumarin in cinnamon have prompted numerous investigations as well, as its presence is suspected of being harmful. All of these studies require sample derivatization and long analysis times. In the current study, DART-MS was used to analyze cinnamon and detect the presence of coumarin. Showing 0 Comment Comments are closed.