JMS-S3000 SpiralTOF™-plus Product Brochure The JMS-S3000 SpiralTOF™-plus Ultra-High Mass Resolution MALDI-TOFMS System time-of-flight optics design utilizes a figure-eight ion trajectory to allow a 17m flight path to fit in an extremely small console. February 15, 2022 Application Note, MALDI SpiralTOF™, MALDI SpiralTOF™-TOF, Mass Spectrometry (MS), Product Brochures (MS) 0 Comment Read More >>
Analysis of Degraded Polymethyl Methacrylate by UV Irradiation - MSTips 324 Polymers can be degraded by the effects of light, oxygen, heat, etc. so it is important to understand how the polymer structures change during degradation. Pyrolysis gas chromatograph quadrupole mass spectrometer (Py-GC-QMS) and matrix-assisted laser desorption/ionization time-of-flight mass spectrometer (MALDI-TOFMS) are powerful tools for analyzing polymeric materials. Py-GC-QMS is a method that instantaneously heats a sample with a pyrolyzer and then analyzes the pyrolysis products by GC-MS. Since most of the pyrolysis products are related to monomers and dimers, this technique allows for easy identification of the polymer substructures which is useful for identifying changes to the polymer when degradation occurs. MALDI-TOFMS involves a soft ionization technique that can directly ionize and analyze the intact polymer molecules and often produces singly-charged ions even for high molecular weight compounds. As a result, the m/z axis of the mass spectrum is equal to the mass of the ions, thus making it easy to interpret polymer distributions. Additionally, when MALDI is used with a high-resolution TOFMS, the accurate mass of each ion in the polymer series can be used to calculate their elemental compositions. Moreover, the molecular weight distribution of polymers can be calculated from the ion intensity distribution. In this work, we used Py-GC-QMS and high-resolution MALDI-TOFMS to evaluate the effects of UV irradiation on polymethyl methacrylate (PMMA). December 13, 2021 Application Note, GC Single-Quad MS, MALDI SpiralTOF™, Mass Spectrometry (MS) 0 Comment Read More >>
MALDI imaging brochure Advanced statistical analysis of MALDI MS imaging data required by SpiralTOF-plus while taking full advantage of its high mass-resolving power. March 19, 2021 Application Note, MALDI Imaging, MALDI SpiralTOF™, Mass Spectrometry (MS), Product Brochures (MS) 0 Comment Read More >>
SpiralTOF-plus Polymer Mass Spectra Collection Applications concerning Polymers using the SpiralTOF. March 11, 2021 Application Note, MALDI SpiralTOF™, Mass Spectrometry (MS) 0 Comment Read More >>
SpiralTOF Polymers, Materials & Chemistry Applications Notebook 2020 Applications concerning Polymers, Materials & Chemistry using the SpiralTOF. March 11, 2021 Application Note, MALDI SpiralTOF™, Mass Spectrometry (MS) 0 Comment Read More >>
SpiralTOF Life Science Applications Notebook 2020 Applications for Life Science using the SpiralTOF. March 11, 2021 Application Note, MALDI SpiralTOF™, Mass Spectrometry (MS) 0 Comment Read More >>
Fraction base-KMD plots for a high-MW - S3000 - MSTips - 283 High molecular weight polymers are often MS-silent due to their inherent high dispersity (DM) or detected in the high mass range with low resolving power. An "on-plate" alkaline degradation has thus been developed as a sample pre-treatment on the MALDI target with tenths of ng of polymer to cut long industrial polyester chains into short oligomers amenable to MALDI-HRMS. July 27, 2020 Application Note, MALDI SpiralTOF™, Mass Spectrometry (MS) 0 Comment Read More >>
Introduction of the JMS-3000 SpiralTOF - Analysis of Bovine Serum Albumin The JMS-S3000 "SpiralTOF™" is a MALDI-TOF MS incorporating an innovative SpiralTOF™ ion optics system. JEOL's patented technology achieves a spiral ion trajectory of 17m within a compact 1m space. July 27, 2020 Application Note, MALDI SpiralTOF™, MALDI SpiralTOF™-TOF, Mass Spectrometry (MS) 0 Comment Read More >>
High Sensitivity Analysis of Intact Proteins using Linear TOF The JMS-S3000 SpiralTOF has a unique 17m flight path that offers then highest resolution MALDI-TOF MS system currently available. However, ions with a very short lifetime or that undergo spontaneous dissociation during their flight cannot be detected by the SpiralTOF (or a conventional reflection TOF). To address this situation, the SpiralTOF with Linear TOF option can be used for the high sensitivity analysis of intact proteins. July 27, 2020 Application Note, MALDI SpiralTOF™, Mass Spectrometry (MS) 0 Comment Read More >>
Proteins using spiral mode S3000 - MSTips 297 In this study, we used the JMS-S3000 to test several matrices for PSD effects and to measure high resolution mass spectra of intact insulin, ubiquitin and cytochrome C. June 12, 2020 Application Note, MALDI SpiralTOF™, Mass Spectrometry (MS) 0 Comment Read More >>