JEOL Resources | MALDI SpiralTOF™

Analysis of degraded polystyrene by UV irradiation using high-resolution MALDI-TOFMS and pyrolysis-GC-QMS

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1 MIN READ |
53 |
July 30, 2026 |
AccuTOF™ GC, MALDI SpiralTOF™, Mass Spectrometry (MS), MS Application Notes |

In this work, we used Py-GC-QMS and high-resolution MALDI-TOFMS to evaluate the effects of UV irradiation on polystyrene (PS).

Improvement of Mass Spectrometry Imaging Capability in JMS-S3000 "SpiralTOF™-plus"

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2 MIN READ |
45 |
July 30, 2026 |
MALDI SpiralTOF™, Mass Spectrometry (MS), MS Application Notes |

In the fall of 2019, SpiralTOF™ was renewed to "SpiralTOF™-plus" with enhanced mass spectrometry imaging capabilities while maintaining the feature of high mass-resolving power. This report introduces the features of SpiralTOF™-plus and its advantages in actual analysis.

Analysis of a drug in urine by JMS-S3000 "SpiralTOF™" and TOF-TOF option

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1 MIN READ |
70 |
July 24, 2026 |
MALDI SpiralTOF™, Mass Spectrometry (MS), MS Application Notes |

In this report, we analyzed methylephedrine, a phenethylamine compound, in common cold medicines as an application to the field of forensic chemistry.

Measurement examples of organic pigments using Laser Desorption/Ionization (LDI) and Field Desorption (FD)

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1 MIN READ |
61 |
July 24, 2026 |
MALDI SpiralTOF™, Mass Spectrometry (MS), MS Application Notes |

In this work, commercially available organic pigments were analyzed using JMS-S3000 SpiralTOF™ and JMS-T200GC AccuTOF™ GCx-plus. Measurements were performed by matrix-free LDI (Laser Desorption Ionization) on the JMS-S3000 and by FD (Field Desorption) on the JMS-T200GC. Because good results were obtained with both methods, we report them here.

Analysis of medicinal properties in a combination cold remedy by using JMS-S3000 "SpiralTOF™"

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1 MIN READ |
67 |
July 24, 2026 |
MALDI SpiralTOF™, Mass Spectrometry (MS), MS Application Notes |

In this report, we will discuss the analysis of medicinal components in a combination cold remedy.

MALDI-ISD Measurements Using Both the SpiralTOF Mode and the LinearTOF Mode of JMS-S3000 “SpiralTOF™”

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1 MIN READ |
73 |
July 23, 2026 |
MALDI SpiralTOF™, Mass Spectrometry (MS), MS Application Notes |

Matrix-assisted laser desorption/ionization (MALDI) combined with in-source decay (ISD) is a useful tool for doing top-down sequencing of intact proteins. In this work, we measured and compared the ISD fragment ions generated for several proteins using the high resolution MALDI- Spiral mode and the high sensitivity MALDI-Linear mode available on the JEOL SpiralTOF MALDI-MS system.

High Sensitivity Analysis of intact Proteins Using Linear TOF

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1 MIN READ |
80 |
July 23, 2026 |
MALDI SpiralTOF™, Mass Spectrometry (MS), MS Application Notes |

In this work, we demonstrate the measurement of intact proteins by using the Linear TOF option for the JEOL SpiralTOF system.

Analysis of cyanoacrylate adhesive using the JMS-S3000 “SpiralTOF™” — Application of Kendrick Mass Defect plot analysis

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1 MIN READ |
81 |
July 20, 2026 |
MALDI SpiralTOF™, Mass Spectrometry (MS), MS Application Notes |

Recently, Kendrick mass defect (KMD) plot analysis has been proposed as an effective data processing technique for SpiralTOF™ which allows for the structural characterization of complicated compounds1, 2. Here, a commercial acrylic adhesive containing cyanoacrylate was characterized using a SpiralTOF™ combined with KMD plot analysis.