Experimental: Samples were analyzed by using a MALDI/TOF-TOF (JEOL JMS-S3000 “Spiral TOF™ MS”) mass spectrometer with multi-turn ion optics that fit a 17-meter flight path within a 1 meter space. Electrostatic sectors are used to continuously refocus the ion beam to minimize ion losses. The MS-I resolving power is sufficiently high (60,000 FWHM) that monoisotopic precursor selection can be achieved by using a simple deflector. Ions with 20 keV kinetic energies undergo collisions with helium and a 9 keV post-acceleration combined with an offset parabolic reflector provides a wide energy acceptance for product ions. Irganox1010 added to PMMA solution was used as a model sample, which included 5000 ppm as concentration of Irganox1010. 2,5-Dihydroxybenzoic acid (DHB) was used as the MALDI matrix and sodium iodide (NaI) was used as cationization agent.