Analytical Instrument Documents

JEOL Resources

rss

Documentation in support of your JEOL product.

Qualitative and Comparative Analyses of Impurities in Isopropanol using Two Different GC Columns
Qualitative and Comparative Analyses of Impurities in Isopropanol using Two Different GC Columns
MSTips No.513

General

Isopropanol (IPA), for its superior solubility and volatility, is playing an  indispensable role as a cleaning agent or solvent in the semiconductor industry. Quality control of high purity IPA products directly determines the stability of fabrication processes and the performance of resulting devices, making it necessary to detect and identify trace impurities contained. Because varying impurity compositions among IPA products, which are produced and refined differently, are likely to affect microstructure formation in semiconductor fabrication processes, comparative analysis of different compositions is in increasing demand.

In this work, we conducted a comprehensive analysis of impurities contained in two different commercial IPA products, using a JMS-T2000GC, one of JEOL’s gas chromatography-high resolution mass spectrometers (GC-HRMS). We also used two different GC columns to identify impurity components to examine polarities and diverse molecular structures of the compounds.

Our objective is to prove the effectiveness of the JMS-T2000GC combined with its qualitative analysis software, msFineAnalysis AI, in qualitative analysis of trace organic impurities contained in different IPA samples, so that we can contribute to enhancing the performance level of solvent quality control in semiconductor fabrication.

Attached Files

Other Resources

Walkup NMR
  • See how the Delta NMR software allows users to just "walk up" and start NMR experiments
  • Mass Spec Reference Data
  • View our page of useful molecular references for Mass Spec
  • Tutorials (Mass Spec)
  • Documents on the basics of mass spectrometry
  • Delta NMR software Tutorials
  • Videos on how to use the Delta NMR software
  • No-D NMR
  • Description of No-D NMR and how it can be used to eliminate the need for deuterated solvents
  • Non Uniform Sampling (NUS)
  • Description of how NUS is used to greatly reduce the time needed for running NMR experiments
  • NMR Basics
  • Overview of the Basics of NMR Theory
  • NMR Magnet Destruction
  • See our presentation of the slicing open of a JEOL Delta-GSX 270 MHz NMR Magnet
  • NMR Training
    Basic Operations and System Management for JEOL NMR Users
    Mass Spec Training
    Learn more about spectrometer operation and maintenance, data collection and processing, and advanced MS software operation.
    JEOLink NMR Newsletter
    We publish and send out this NMR newsletter to our customers. They can also be viewed here.
    Mass Media Newsletter
    We publish and send out this Mass Spec newsletter to our customers. They can also be viewed here.
    © Copyright 2026 by JEOL USA, Inc.
    Terms of Use
    |
    Privacy Policy
    |
    Cookie Preferences