“Remainders of KM” plot for polymers using msRepeatFinder: Intuitive display of High energy collision induced dissociation mass spectra acquired by SpiralTOF™/TOF March 5, 2020 Application Note, MALDI SpiralTOF™-TOF, Mass Spectrometry (MS) 0 Product: JMS-S3000 Introduction Tandem mass spectrometry of polymer ions provides valuable information about the nature of individual end-groups, chain architecture (linear / cyclic / branched) and copolymeric microstructure. Using matrix-assisted laser desorption ionization (MALDI) with high energy collision-induced dissociation (HE-CID) tandem time-of-flight analysis (TOF/TOF) can be advantageous for MS/MS polymer analysis. However, the interpretation of the resulting mass spectrum may not be obvious when a number of ion series with low intensity signals are present. In this work, a “remainders of Kendrick mass” (RKM) analysis is used as a rapid post-acquisition data processing tool for TOF/TOF mass spectra in order to visualize and filter the ion series instantly via intuitive point alignments. Experimental Poly(propylene oxide) (PPO 1000 g mol-1) was used for an analyte. Product ion spectra were recorded with a JEOL JMS-S3000 SpiralTOF™ mass spectrometer (CHCA 10 mg mL-1, PPO 10 mg mL-1, NaTFA 1 mg mL-1, 10:1:1 in MeOH). The plots were computed by using msRepeatFinder 3.0 (JEOL Ltd.). For full details: Attached files often contain the full content of the item you are viewing. Be sure and view any attachments. Remainders of KM plot for polymers-HECID - S3000 TOF-TOF - MSTips - 270.pdf 985.26 KB Showing 0 Comment Comments are closed.