Structural Analysis of a High Molecular Weight Peptide March 5, 2020 Application Note, MALDI SpiralTOF™-TOF, Mass Spectrometry (MS) 0 Introduction: The JMS-S3000 SpiralTOF™ is a MALDI-TOF MS that uses an innovative spiral ion optics system to achieve the highest resolution currently available for a MALDI instrument. Additionally, the JMS-S3000 is available with a TOF-TOF option that acquires high-energy collision-induced dissociation (CID) product-ion spectra for monoisotopically selected precursor ions. In this work, we analyzed a high molecular weight peptide by using the JMS-S3000 SpiralTOF with the TOF-TOF option. Experimental: Sample: ACTH18-39 (Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe) Matrix: α-Cyano-4-hydroxycinnamic acid (CHCA) For full details: Attached files often contain the full content of the item you are viewing. Be sure and view any attachments. Apps Note Molecular Weight Peptide.pdf 429.34 KB Showing 0 Comment Comments are closed.