PRODUCTS

Analytical Instrument Documents

JEOL Resources

rss

Documentation in support of your JEOL product.

The AccuTOF time-of-flight mass spectrometer equipped with Direct Analysis in Real Time (DART™) has been used to detect a wide variety of explosives in or on a variety of materials ranging from solutions to samples deposited on surfaces ranging from ABS plastic to metal, clothing and cardboard. Detection is rapid, specific, and sensitive.

Please see the following publication: “Versatile New Ion Source for the Analysis of Materials in Open Air under Ambient Conditions” Robert B. Cody, James A. Laramee and H. Dupont Durst, Analytical Chemistry 77 (8), 2297- 2302, 2005

DART provides very simple mass spectra that are free of multiple charging and alkali metal cation adducts such as [M+Na]+  and [M+K]. This facilitates identification of target compounds in mixtures and simplifies assignment of elemental compositions for unknowns.

Includes 44 application notes in the categories of Introduction and fundamentals, Drug Analysis, [Food, Flavors, and Fragrances], Forensics, Homeland Security, Industrial Materials, and Organic Chemistry.

In a recently published comparison of the ambient ionization techniques direct analysis in real time (DART™) and DESI, it was reported that a protonated molecule was not observed for DART, whereas the protonated molecule could be observed for DESI and DAPCI. This is an incorrect observation, resulting from the use of different experimental conditions for DART than were used for the other two techniques. Mass spectra of aspirin measured on a JEOL AccuTOF-DART™ mass spectrometer under the correct operating conditions are shown here. All assignments for the mass spectral peaks were confirmed by exact mass measurements.

Methamphetamine is a Schedule II Controlled Substance that is illegally manufactured in clandestine labs. There are several common synthetic pathways in use. For this study, methamphetamine was synthesized from phenyl-2-propanone by the (1) Leukart synthesis or (2) Reductive Amination, or from ephedrine or pseudoephedrine by the (3) Nagai, (4) Birch, and (5) Edme syntheses. Each of these reaction sequences resulted in unique impurity profiles1-3 that can be used by law enforcement to track the activities of clan labs, distribution networks, and trafficking patterns. The AccuTOF-DART was used to examine the starting materials, reaction mixtures, and final products from each reaction scheme.

DART provides a convenient means for monitoring the progress of chemical reactions. Reactants, intermediates, products and byproducts can be detected by simply dipping a glass rod into the reaction pot and then placing the rod in front of the DART ion source. The AccuTOF's ability to measure accurate masses and isotopic abundances makes it possible to confirm or identify the elemental compositions of peaks in the mass spectra. Here we show the use of AccuTOF-DART to monitor the acetylation of 1,2-hexanediol as a function of time.

Fingerprints contain a great deal of chemical information that is not often exploited for forensic analysis. DART can detect and identify the chemical components of fingerprints, often providing information about what substances a subject has been handling.

Strobilurins, systemic pesticides originated from natural fungicidal derivatives, play an important role in control of various plant pathogens. Because of their unique protective properties, significant yield enhancements and longer retention of green leaf tissue, strobilurins have been widely used in agriculture since their introduction on the market in 1992. As other pesticides, these compounds are involved in control and monitoring surveys undertaken by regulation authorities.

DART can ionize organic substance on solid surface in atmospheric pressure. By utilizing this feature, we analyzed organic contaminant adhered to a metal part.

Other Resources

Image Gallery
  • View a selection of NMR and MS spectra
  • Walkup NMR
  • See how the Delta NMR software allows users to just "walk up" and start NMR experiments
  • Mass Spec Reference Data
  • View our page of useful molecular references for Mass Spec
  • Tutorials (Mass Spec)
  • Documents on the basics of mass spectrometry
  • Delta NMR software Tutorials
  • Videos on how to use the Delta NMR software
  • No-D NMR
  • Description of No-D NMR and how it can be used to eliminate the need for deuterated solvents
  • Non Uniform Sampling (NUS)
  • Description of how NUS is used to greatly reduce the time needed for running NMR experiments
  • NMR Basics
  • Overview of the Basics of NMR Theory
  • NMR Magnet Destruction
  • See our presentation of the slicing open of a JEOL Delta-GSX 270 MHz NMR Magnet
  • Media

    Corona - Glow Discharge (DART Ion Source)

    January 28, 2022
    2448
      JEOL USA, Inc.
      11 Dearborn Road
      Peabody, MA 01960
      © Copyright 2022 by JEOL USA, Inc.