Analysis of Scotch Whiskey and Tequila Samples by Solid-Phase Microextraction and High-Resolution GC/MS March 5, 2020 Application Note, GCmate™, Mass Spectrometry (MS) 0 Summary Solid-phase microextraction (SPME) is a convenient sample preparation method for extracting organic compounds from aqueous samples. The combination of SPME with gas chromatography and high-resolution mass spectrometry provides powerful capabilities for the analysis of alcoholic beverages. Two samples of Scotch whiskey and one tequila sample were sampled by using solid-phase microextraction for analysis by high-resolution GC/MS. Sample 1 was a blended 12-year old light Scotch whiskey, while sample 2 was a 12-year old single-malt light Scotch whiskey. The tequila sample was a popular brand that is widely sold in the USA. Compounds were extracted and identified by GC/MS with library search. Exact mass measurements provided elemental compositions for molecular ions and fragment ions. Solid-Phase Microextraction A Supelco 2cm-50/30μm DVB Carboxen/PDMS StableFlex SPME Fiber Assembly mounted in a manual SPME holder was immersed in each sample for approximately 5 minutes and then desorbed into the GC injector port at 250°C for 2 minutes. For full details: Attached files often contain the full content of the item you are viewing. Be sure and view any attachments. SPME1.pdf 477.68 KB Showing 0 Comment Comments are closed.