GCxGC TOFMS Analysis of Base Oils with CI, PI, FI March 4, 2020 AccuTOF™ GC, Application Note, GCxGC, Mass Spectrometry (MS), Petroleum 0 Introduction Structural elucidation of hydrocarbon classes in petroleum products are always in high demand. Comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GCxGC-TOFMS) with electron ionization (EI) is a powerful method for characterizing complex mixtures such as base oils. However, EI data can often lack a strong molecular ion signal. Therefore, it is necessary to measure samples with soft-ionization methods such as positive chemical ionization (PCI), field ionization (FI), or photo-ionization (PI) for the detection of molecular ions. Each technique is a little different so it is important to understand the characteristics of each soft ionization method. In this application note, we compare the mass spectra of a base oil analyzed by GCxGC-TOFMS with EI, PCI, FI, and PI. Experiment The details for sample dilution in hexane as well as the instrumental conditions are listed in Table 1. For full details: Attached files often contain the full content of the item you are viewing. Be sure and view any attachments. GCxGC Analysis of Base Oils with CI FI PI.pdf 342.05 KB Related Articles GC-TOFMS Application: Natural Polymer Analysis by using Pyrolysis-GCxGC-MS - "Urushi" analysis with GCxGC/EI and GCxGC/PI A Japanese lacquer film called "Urushi" is a natural polymer that has been used as a paint and adhesive for living-wares and craft-wares for approximately 8,000 years. "Urushi" has a complex structure that researchers are trying to understand using pyrolysis-gas chromatograph/mass spectrometer (Py/GC/MS) system. Recently, we developed a new gas chromatograph/high resolution time-of-flight mass spectrometer (GC/HR-TOFMS) system that can be used for comprehensive two-dimensional GC (GCxGC) measurements. Additionally, we have developed a unique combination electron ionization/photoionization (EI/PI) ion source that can be used with this GC/HR-TOFMS system. In this work, we measured "Urushi" samples using this unique Py/GCxGC/HR-TOFMS system in combination with our new combination EI/PI ion source. Comprehensive 2D GC coupled with JEOL GC-HRTOFMS: GCxGC Applications Diesel Fuel Analysis by GCxGC/EI (Hydrocarbon Classification); Biomarker Analysis by GCxGC/PI (Target Analysis using 2D EICC); Type Analysis by GCxGC/FI (Hydrocarbon Type Analysis); Synthetic Polymer Analysis by Pryolysis GCxGC/EI and FI (Unknown Compounds Analysis in Nylon 66); Additives Analysis by Pyrolysis GCxGC/EI and FI (Targeted Additives Analysis in Nitrile Butadiene Rubber); Natural Polymer Analysis by Pyrolysis GCxGC/EI and PI (Powerful Separation of the Main Components in a Japanese Lacquer Film); Soluble Organic Fraction Analysis by GCxGC/EI (Analysis of PAHs in Exhaust Gas); Electronic Waste Analysis by GCxGC/EI and Negative CI (Halogenated Compounds Analysis); Aroma Oil (Fragrance) Analysis by GCxGC/EI and FI (Molecular ion detection for Alcohol compounds); Sebum Analysis by GCxGC/EI (Pharmaceutical application) Using GCxGC/HRTOFMS with EI/FI/PI for component identification and time variation analysis of perfume Perfumes are known to be complex mixtures that typically contain a variety of compounds. Their scents are strongly affected by these compounds and their quantity ratios. Additionally, these ratios can change over time, thus changing the perfume’s scent. Two-dimensional gas chromatography/time-of-flight mass spectrometry (GCxGC-TOFMS) is an effective technique for measuring complex samples like perfumes. Using electron ionization (EI) allows for database searches. However, these searches may result in mis-assignments without the additional high-resolution molecular ion information that can be generated through soft ionization techniques. In this study, we used GCxGC-HRTOFMS with EI and the soft ionization techniques of FI (Field Ionization) and PI (Photoionization). Additionally, we measured the changes in intensity over time for the top note/middle note/base note compounds. Analysis of Electronics Waste by GCxGC Combined with High-resolution Mass Spectrometry: Using Accurate Mass Information and Mass Defect Analysis to Explore the Data Comprehensive two-dimensional gas chromatography (GCxGC) in combination with high-resolution mass spectrometry (HRMS) is a powerful tool for the analysis of complex mixtures. However, new software tools are required to facilitate the interpretation of the rich information content in GCxGC/HRMS data sets. In this work, we analyzed a dust sample collected from an electronics recycling facility by using GCxGC in combination with a new high-resolution time-of-flight (TOF) mass spectrometer. Nontraditional Kendrick Mass Defect (KMD) plots were used to identify halogenated contaminants in an electronics waste sample. Database search results combined with elemental composition determinations from exact-mass data were used to identify (potential) persistent organic pollutants (POPs). Analysis of Diesel Oil by Using GCxGC-HRTOFMS (FI) with 2 Different Sets of Column Combinations Comprehensive two-dimensional gas chromatography (GC×GC) is a kind of continuous heart-cut GC system. Two different types of columns are connected via a modulator in the same GC oven. By using the two columns together, this technique provides very high separation capabilities when compared to one- dimensional GC analysis. This report shows the difference of separation result for diesel oil when 2 different sets of combined columns are used with GC×GC-HRTOFMS (FI). SPME-GCxGC/HRTOFMS Analysis of Tequila The JEOL “AccuTOF GCv 4G” is a third generation GC/HRTOFMS system with high speed data acquisition capabilities of up to 50Hz which makes it well suited as the detector for comprehensive 2-dimensional GC (GCxGC) measurements. Along with the high speed data acquisition, this MS system also provides high mass resolution, accurate mass measurements, and high sensitivity, all simultaneously. Consequently, this GCxGC/HRTOFMS system is a powerful tool for the qualitative analysis of complicated samples. In this work, we measured commercially available tequila samples using GCxGC/HRTOFMS combined with solid-phase micro-extraction (SPME) preparation. Showing 0 Comment Comments are closed.