Analytical Instrument Documents

GC-Alpha combines high-resolution accurate mass, multiple ionization techniques, comprehensive GC×GC capability, and AI-assisted structural analysis to help scientists identify unknown compounds and better understand complex samples with speed and confidence.

One of the biggest analytical challenges is the complexity of pyrolysis oil. It contains hundreds of compounds with different chemical properties, many of which are unknown or present at very low concentrations. These complex mixtures are often difficult to fully characterize using conventional GC-MS because compounds can co-elute, complicating separation and identification.

By selecting the appropriate combination of GC separation, hard ionization, soft ionization, and direct MS measurement, scientists can obtain a more complete view of complex hydrocarbon samples than would be possible using a single method alone.

Multinuclear NMR is a powerful analytical technique that enables the observation of a wide variety of nuclei such as15N, 11B, 19F, and 31P. However, because each nucleus has distinct sensitivity, relaxation properties, and measurement requirements, an understanding of proper instrument setup and experimental conditions is essential for obtaining reliable results. In this column, we will explain the key points necessary for successful multinuclear NMR experiments such as the fundamentals of multinuclear NMR, the factors that influence detection sensitivity, and pulse conditions in a clear and accessible manner.

To more comprehensively evaluate the oblique-light degradation characteristics of indoor line tapes, qualitative analysis of outgassed components was performed using thermal desorption–GC/MS. As a result, compounds presumed to originate from migration from the floor surface materials were detected. To ensure the validity of the evaluation results, these migrated components were assessed prior to the oblique-light degradation study, and the findings are presented below.

In this paper, we focus on the gases generated during the charging and discharging of all-solid-state batteries and present an example of analysis using a mass spectrometer.

We have introduced the oxygen-resistant filament application note for QMS in MSTips No. 320. In this MSTips, we introduce anti-oxygen filament application data for high-resolution TOFMS.

JEOL Ltd. released the 6th generation high-end GC-QMS "JMS-Q1600GC UltraQuad™ SQ-Zeta" in 2021. We report on the construction of a system that enables measurement of all GC-MS items of water quality standards with a single instrument using the JMS-Q1600GC. The system can measure all test items without the need for column replacement by connecting a mid-polar column and a non-polar column to one JMS-Q1600GC in a double column configuration. In addition, by using the new attachment "High-Performance Ion Source (EPIS)", an easier "Scan quantification" is possible instead of the "SIM quantification" that requires complicated condition settings. This MSTips reports the results of the evaluation of the linearity of the calibration curves for each item and the repeatability at a lower concentration limit.

Results using the EI method are reported in MSTips 343. In this report, we describe a highly sensitive negative ion measurement method by TG-MS using the Electron Capture Ionization (ECI) method. In addition to selective detection of molecular ions, which is a feature of the soft ionization method, the ECI method can selectively detect oxygen, sulfur, and various halogen compounds with high electronegativity, a feature of the negative ionization method. Therefore, the ECI method is considered to be effective for the analysis of trace constituents.

Thermogravimetric-Mass Spectrometry (TG-MS) is effective for the analysis of synthetic rubber because it is possible to correlate and obtain on the weight loss and qualitative information on the generated gas when heating is applied. On the other hand, since this method does not use chromatogram separation, many rubber pyrolysis products (mainly hydrocarbons) make it difficult to analyze trace components. Therefore, mass separation by high-resolution TOFMS JMS-T2000GC was performed and useful results were obtained. While this report presents the results of the EI method, MSTips 344 reports the results of the Electron Capture Ionization (ECI) method.