Analytical Instrument Documents

In this report, we report the statistical analysis of high-mass resolution MALDI-MSI data of various lipids in biological samples.

SpiralTOF™-plus 2.0 with TOF-TOF option can achieve high precursor ion selectivity due to the long flight path of the spiral ion optics used in the 1st TOFMS. In this application note, we report the structural elucidation of a photodegradation product of reserpine as an example of structural analysis of a component close to a possible interference in mass by MS/MS measurement using the SpiralTOF™-plus 2.0 with TOF-TOF option.

Molecular weight confirmation of synthesized oligonucleotides is important for the quality control of pharmaceuticals. In this report, we used the synthesized oligonucleotide (Table 1) as a sample and measured it with a MALDI-TOFMS.

Coffee aroma contains a very large number of components. Therefore, a large number of peaks are observed in TIC chromatogram, and it takes a long time to identify the components of each peak and to analyze differences between samples. In this report, we present the results of differential and integrated analyses performed on coffee aroma components using msFineAnalysis iQ.

We report the results of the integrated qualitative analysis combining library database search and molecular ion confirmation when performing msFineAnalysis iQ.

Recently, it has been possible to efficiently overview the information in the mass spectra of complex polymer mixtures using a Kendrick Mass Defect (KMD) analysis software, msRepeatFinder. Determining the elemental composition of the end groups of the polymer series identified in this way is essential for confirming the state of polymer synthesis reactions, quality control of products, and analysis of degradation mechanisms. In this report, we introduce the procedure for determining the elemental compositions of the end groups from the accurate mass information of the polymer.

In MSTips No. 355, the effectiveness of the FD method in additive analysis was shown using an analysis example of bromine flame retardant in polypropylene products. In this report, we introduce an analysis example of molybdenum dithiocarbamate (MoDTC), which is a friction reducing agent for lubricating oil.

This report shows the result of analysis for two types of polypropylene (PP) products. The difference between sample was not found by the pyrolysis method, but a brominated flame retardants was found as a difference by the FD method.

By gradual heating, unlike Py/GC/MS, moderately fragmented oligomer components can be analyzed by DART-MS. Some of the oligomer components generated include the end group structure by single cleavage of the main chain, which helps to analyze the structure of the polymer. Here, an analysis example of polyphenylene sulfide (PPS) using TDP-DART-MS is reported [2]. PPS is an engineering plastic with excellent heat resistance and chemical resistance. It is important to analyze the structure of the end groups because the difference in the manufacturing method appears in the end groups. However, it was difficult to analyze the end groups of PPS because it is insoluble in general organic solvents.

In this study, it was hypothesized that material degradation under oblique-light conditions would affect the composition and release behavior of outgassed components. Accordingly, differential analysis of outgassed components before and after oblique-light degradation was carried out using thermal desorption–GC/MS.