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Structural analysis of PET combining an on-plate alkaline degradation method & tandem TOFMS - MSTips 311

We investigated the structural analysis of the polyethylene-terephthalate (PET) polymer exposed to the on-plate alkaline degradation method by using the JMS-S3000 "SpiralTOFTM-plus" with TOF-TOF option. The SpiralTOFTM-plus uses an ultra-high resolution TOF for MS1 which allows monoisotopic precursor selection and a reflectron TOF for MS2 to analyze the product ion spectra produced from high energy collisional induced dissociation (HE-CID).

Structural Analysis of Triacylglycerols by Using a MALDI-TOF/TOF System with Monoisotopic Precursor Selection

A new MALDI-TOF/TOF system with monoisotopic precursor selection was applied to the analysis of triacylglycerols in an olive oil sample. Monoisotopic precursor selection made it possible to obtain product-ion mass spectra without interference from species that differed by a single double bond. Complete structure determination of all triacylglycerols, including structural isomers, was made possible by interpreting the charge-remote fragmentation resulting from high-energy collision-induced dissociation (CID) of the sodiated triacylglycerols.

Visualizing fragmentation channels of polyethylene oxide with different end groups using the JMS-S3000 SpiralTOFTM with TOF–TOF option

Tandem mass spectrometry is a powerful tool for polymer characterization. It can obtain information about polymer end groups, repeating structures (linear, cyclic, or branched), and copolymerization. High-energy collision–induced dissociation (HE-CID) is a fragmentation method that is available only in tandem time-of-flight mass spectrometry (TOF–TOF). The informative fragmentation channels, which are difficult to observe with commonly used low-energy CID, are often observable in HE-CID spectra. In MSTips 270, we proposed a method to visualize this abundant structural information and enable intuitive analysis using the “Remainders of KM” (RKM) plot method. In this report, we applied the method to analyze polyethylene oxide (PEO) with different end groups.

Synthetic Polymer Structure Analysis: Poly Methal Methacrylate (PMMA)

The JMS-S3000 “SpiralTOF™” is a MALDI-TOFMS that incorporates an innovative SpiralTOF ion optics system. This system is available with a TOF-TOF option that can acquire high-energy collision-induced dissociation (CID) product ion spectra for monoisotopically selected precursor ions. In this work, we analyzed Poly Methyl Methacrylate (PMMA) shown in Fig. 1 by using the JMS-S3000 SpiralTOF with the TOF-TOF option. The resulting high-energy CID data was then processed using the Polymerix™ (Sierra Analytics, Inc., http://massspec. com/) analysis software.

Structure analysis of a polymer additive using high-energy collision–induced dissociation mass spectra acquired by SpiralTOFTM/TOF

Various kinds of additives are used in a polymer, such as an antioxidant, a light stabilizer, and an ultraviolet absorber. Because a polymer’s properties depend on the additives in the raw material, it is important to understand these additives. Matrix-assistance laser desorption/ ionization time-of-flight mass spectrometer (MALDI-TOFMS) JMS-S3000 SpiralTOF™ is widely used in polymer analysis. High-energy collision–induced dissociation (HE-CID) measurement with the TOF-TOF option is also useful in analyzing the structures of additives. SpiralTOF™ can achieve a high precursor ion selection with a revolution of 17 m. Fragmentation derived from HE-CID can be observed only due to the ions from post-source decay (PSD), these fragment ions can be eliminated by the four electrostatic sectors that constitute the spiral trajectory. In this Applications Note, we report on polymer structural analysis by compare fragmentation patterns in the product ion spectra of IRGANOX 1076 M+・ and [M+Na]+.

Structural Analysis of Tristearin

The JMS-S3000 SpiralTOF™ is a MALDI-TOF MS that uses an innovative spiral ion optical system to achieve the highest resolution currently available for a MALDI instrument. Additionally, this system can be equipped with a TOF-TOF option that can acquire high-energy collisioninduced dissociation (HE-CID) product ion spectra for monoisotopically selected precursor ions. The resulting HE-CID product ion spectra provide detailed structural information about compounds like triglycerides by means of charge-remote fragmentation (CRF).1 Tristearin is a triglyceride found in fats that consists of three stearic acid moieties (Fig. 1). In this work, we report the structural analysis of tristearin by using the HE-CID capabilities of the SpiralTOF-TOF.

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Corona - Glow Discharge (DART Ion Source)

February 22, 2020
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